Amyloid and Amyloidosis
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AMYLOID AND AMYLOID0SIS EDITED BY
TAKASH I ISO BE Kobe University Kobe, Japan
SHUKURO ARAKI Kumamoto University Kumamoto, Japan
FUMIYA UCHINO Yamaguchi University Ube, Japan
SHOZO KITO Hiroshima University Hiroshima, Japan
AND
EIRO TSUBURA Toneyama National Hospital Toneyama, Japan
SPRINGER SCIENCE+BUSINESS MEDIA, LLC
library of Congress Cataloging in Publication Date International Symposium on Amyloidosis (5th: 1987: Hakone-machi, Japan) Amyloid and amyloidosis I edited by Takashi lsobe ... [etal.]. p. cm. "Proceedings of the Fifth International Symposium on Amyloidosis, held October 25-28, 1987, in Hakone, Japan"-T.p. verso. Bibliography: p. lncludes index. ISBN 978-1-4757-0300-9 ISBN 978-1-4757-0298-9 (eBook) DOI 10.1007/978-1-4757-0298-9 1. Amyloidosis-Congresses. I. lsobe, Tokashi, date. II. Tifte. RC632.A5157 1987 616.3'995-dc 19
88-22425 CIP
Proceedings of the Fifth International Symposium on Amyloidosis, held October 25-28, 1987, in Hakone, Japan
© 1988 Springer Science+Business Media New York Originally published by Plenum Press New York in 1988 Softcover reprint of the herdeover 1st edition 1988
All rights reserved No part of this book may be reproduced, stared in a retrieval system, ar Iransmitted in any form or by any means, electronic, mechanical, photocopying, microfilming, recording, or otherwise, without written permission from the Publisher
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The final answer, I know, is always inside. But the outside can give a clue, can help one to find the inside answer. 11 from
GIFT FROM THE SEA
INTRODUC TI ON One afternoon during the symposium, a magnificent view of Mt. Fuji covered with snow captured the attention of most people taking a break during the meeting at the shore of Lake Ashi at Hakone. The darkness and heavy rain seen through the windows the night before thus gave way to a completely different view. Clearing of the weather seemed to parallel the history of amyloid research. From the gloomy era of old-fashioned case reports, we now faced a high mountain of new knowledge an amyloidosis. The purpese of this book is to record the memorable achievements of all those who participated in the Fifth International Symposium on Amyloidosis in October 1987. A cordial welcome was extended to participants from different countries and different areas of involvement in amyloid research. The 147 manuscripts in these proceedings attest to the success and stimulated scientific discussions held at our Hakone reunion. The sturlies presented at this symposium covered conventional clinical, experimental, morphological, physicochemical, biochemical and immunochemical subjects. They also included genetic analyses relevant to different aspects of the disease. This certainly represents the biggest advance in amyloiodosis research in recent years. Recognizing that amyloid deposits may play a significant role in diverse conditions, considerable attention was given to the area of cerebral amyloid, including Alzheimer' s Disease. Diversity of results abtairred in the field of familial amy
