Amyloidosis Diagnosis and Treatment
An up-to-date reference on this fascinating set of complex disorders, this book features the most comprehensive strategies for diagnosing, classifying, imaging, treating, and managing amyloidosis in multiple organ systems. Beneficial to the spectrum of pr
- PDF / 4,104,849 Bytes
- 243 Pages / 596.17 x 846.4 pts Page_size
- 43 Downloads / 230 Views
AMYLOIDOSIS: DIAGNOSIS AND TREATMENT Edited by
Morie A. Gertz, MD S. Vincent Rajkumar, MD
Amyloidosis
CONTEMPORARY HEMATOLOGY
Judith E. Karp, S ERIES E DITOR
For other titles published in this series, go to www.springer.com/series/7681
Amyloidosis Diagnosis and Treatment
Edited by
Morie A. Gertz Mayo Clinic Rochester, MN USA
S. Vincent Rajkumar Mayo Clinic Rochester, MN USA
Editors Morie A. Gertz Mayo Clinic 200 First Street SW Rochester, MN 55905 USA [email protected]
S. Vincent Rajkumar Mayo Clinic 200 First Street SW Rochester, MN 55905 USA [email protected]
ISBN 978-1-60761-630-6 e-ISBN 978-1-60761-631-3 DOI 10.1007/978-1-60761-631-3 Springer New York Dordrecht Heidelberg London Library of Congress Control Number: 2010927445 © Springer Science+Business Media, LLC 2010 All rights reserved. This work may not be translated or copied in whole or in part without the written permission of the publisher (Humana Press, c/o Springer Science+Business Media, LLC, 233 Spring Street, New York, NY 10013, USA), except for brief excerpts in connection with reviews or scholarly analysis. Use in connection with any form of information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed is forbidden. The use in this publication of trade names, trademarks, service marks, and similar terms, even if they are not identified as such, is not to be taken as an expression of opinion as to whether or not they are subject to proprietary rights. While the advice and information in this book are believed to be true and accurate at the date of going to press, neither the authors nor the editors nor the publisher can accept any legal responsibility for any errors or omissions that may be made. The publisher makes no warranty, express or implied, with respect to the material contained herein. Printed on acid-free paper Humana Press is part of Springer Science+Business Media (www.springer.com)
Preface
Amyloidosis is a term that represents a wide spectrum of protein folding disorders. The disease may be localized or systemic. The systemic amyloidoses can be either immunoglobulin light chain derived, related to the deposition of amyloid A protein in chronic inflammatory conditions, or an inherited disorder usually related to mutant transthyretin. Normal proteins are known to misfold into amyloid, the clinically most important being native transthyretin in the form of senile systemic amyloidosis. This text attempts to comprehensively provide a framework to clinicians seeing these patients and scientists studying the disorder, with an in-depth treatment of selected world’s literature, as well as newest developments in the disorder. Because amyloidosis is so rare, many practicing clinicians are uncomfortable in the diagnosis, management, classification, prognostication, and therapy of the amyloidoses. This book calls on the clinical and scientific expertise of the world’s noted experts in the protein folding disorders. To understand the
Data Loading...
