An oral cancer biobank initiative: a platform for multidisciplinary research in a developing country
- PDF / 252,414 Bytes
- 8 Pages / 547.087 x 737.008 pts Page_size
- 75 Downloads / 215 Views
An oral cancer biobank initiative: a platform for multidisciplinary research in a developing country Rosnah Binti Zain • Vimmitra Athirajan • Wan Maria Nabillah Ghani • Ishak Abdul Razak • Raja Jalaludin Raja Latifah • Siti Mazlipah Ismail • Atiya Abdul Sallam • Anita Zarina Bustam • Zainal Ariff Abdul Rahman Adam Hussien • Norain Talib • Sok Ching Cheong • Amin Jallaludin
•
Received: 6 October 2011 / Accepted: 15 February 2012 / Published online: 29 February 2012 Ó Springer Science+Business Media B.V. 2012
Abstract Identification of diagnostic markers for early detection and development of novel and therapeutic agents for effective patient management are the main motivation for cancer research. Biological specimens from large cohort and case-control studies which are crucial in providing successful research outcomes are often the limiting factor that hinders research efforts, especially in developing countries. Therefore, the Malaysian Oral Cancer Database and Tissue Bank System (MOCDTBS) were established to systematically collect large number of samples with comprehensive sociodemographic, clinicopathological, management strategies, quality of life and
associated patient follow-up data to facilitate oral cancer research in Malaysia. The MOCDTBS also promotes sharing among researchers and the development of a multidisciplinary research team. The following article aims to describe the process of setting-up and managing the MOCDTBS.
R. B. Zain (&) V. Athirajan W. M. N. Ghani I. A. Razak R. J. Raja Latifah S. M. Ismail A. A. Sallam Oral Cancer Research and Coordinating Centre, Faculty of Dentistry, University Malaya, 50603 Lembah Pantai, Kuala Lumpur, Malaysia e-mail: [email protected]
A. Z. Bustam Dean’s Office, Faculty of Medicine, University Malaya, Kuala Lumpur, Malaysia
Keywords Oral cancer Biobank Malaysia Multidisciplinary team
A. Hussien Department of Restorative Dentistry, School of Dental Sciences, Universiti Sains Malaysia, Kubang Kerian, Kelantan, Malaysia
R. B. Zain Department of Oral Pathology, Oral Medicine and Periodontology, Faculty of Dentistry, University Malaya, Kuala Lumpur, Malaysia
N. Talib Oral Health Division, Ministry of Health, Putrajaya, Malaysia
I. A. Razak Department of Community Dentistry, Faculty of Dentistry, University Malaya, Kuala Lumpur, Malaysia
S. C. Cheong Oral Cancer Research Team, Cancer Research Initiatives Foundation, Kuala Lumpur, Malaysia
S. M. Ismail Z. A. A. Rahman S. C. Cheong Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, University Malaya, Kuala Lumpur, Malaysia
A. Jallaludin Department of Otorhinolaringology, Faculty of Medicine, University Malaya, Kuala Lumpur, Malaysia
123
46
Introduction Increasing efforts have been made worldwide to study the underlying mechanism of cancer and its association with genetic, environmental and lifestyle factors. The understanding of these affords an opportunity to use this information to derive biomarkers for diagnosis, prognosis and therapeutics, which are expected to imp
Data Loading...
