Antimicrobial resistance pattern in domestic animal - wildlife - environmental niche via the food chain to humans with a
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RESEARCH ARTICLE
Open Access
Antimicrobial resistance pattern in domestic animal - wildlife - environmental niche via the food chain to humans with a Bangladesh perspective; a systematic review Shahneaz Ali Khan1*, Mohammed Ashif Imtiaz1, Md. Abu Sayeed2, Amir Hossan Shaikat1 and Mohammad Mahmudul Hassan1
Abstract Background: Antimicrobial resistance (AMR) is a growing concern globally, but the impact is very deleterious in the context of Bangladesh. Recent review article on the AMR issue demonstrates the scenario in human medicine; unfortunately, no attempt was taken to address this as One Health issue. The antimicrobial resistance bacteria or genes are circulating in the fragile ecosystems and disseminate into human food chain through direct or indirect ways. In this systematic review we are exploring the mechanism or the process of development of resistance pathogen into human food chain via the domestic animal, wildlife and environmental sources in the context of One Health and future recommendation to mitigate this issue in Bangladesh. Results: Tetracycline resistance genes were presenting in almost all sample sources in higher concentrations against enteric pathogen Escherichia coli. The second most significant antibiotics are amino-penicillin that showed resistant pattern across different source of samples. It is a matter of concerns that cephalosporin tends to acquire resistance in wildlife species that might be an indication of this antibiotic resistance gene or the pathogen been circulating in our surrounding environment though the mechanism is still unclear. Conclusions: Steps to control antibiotic release and environmental disposal from all uses should be immediate and obligatory. There is a need for detailed system biology analysis of resistance development in-situ. Keywords: AMR, Domestic animals, Wildlife, Insects, Environment, Food chain, Bangladesh
Background Antimicrobial resistance (AMR) is one of the emerging issues globally including in low and middle-income countries (LMICs) for human health threats [1]. Primarily, AMR is the ability of a microbe to avoid the effects * Correspondence: [email protected] 1 Chattogram Veterinary and Animal Sciences University, Zakir Hossain Road,Khulshi, 4225 Chattogram, Bangladesh Full list of author information is available at the end of the article
of an antimicrobial even though exposure to recommended doses. AMR in bacteria can be achieved by several ways including the inherent capability of natural resistance by certain bacteria, genetic mutation or acquired resistance through their surroundings [2]. Bangladesh is a developing and middle-income country in Southeast Asia (SEA) with a dense human population. The presence of diverse wildlife as well as a livestock population (cattle, sheep, goat, and poultry etc.)
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