Antioxidant and antibacterial effects of medicinal plants and their stick-type medicinal concentrated beverages

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Antioxidant and antibacterial effects of medicinal plants and their stick-type medicinal concentrated beverages Hyeon-Jun Chang1 • Yoon-Hee Kim1 • Yun-Hwan Kang2 • Myung-Hwan Choi3 Jeung-Hee Lee1



Received: 22 January 2020 / Revised: 23 May 2020 / Accepted: 6 July 2020 Ó The Korean Society of Food Science and Technology 2020

Abstract Nine medicinal plants and their stick-type medicinal concentrated beverages (SMCB-I and SMCB-II) with different combination ratio were evaluated on antioxidant, nitric oxide (NO) inhibitory, and antibacterial effects against pathogenic bacteria involved in respiratory system illnesses. Antioxidant activity was high in Syzygium aromaticum, Pueraria lobata, Plantago asiatica, and Kalopanax pictus which have higher contents of total phenolics and total flavonoids. The NO inhibitory activity was high in Syzygium aromaticum, Plantago asiatica, and Glycyrrhiza uralensis. Syzygium aromaticum, Plantago asiatica, Kalopanax pictus and Glycyrrhiza uralensis showed higher antibacterial activity than the other five medicinal plants against Staphylococcus aureus, Corynebacterium diphtheriae, and Mycobacterium sp. SMCB-II exhibited higher antioxidant, NO inhibitory, and antibacterial effects than SMCB-I, since Syzygium aromaticum, Pueraria lobata, and Kalopanax pictus were only & Jeung-Hee Lee [email protected] Hyeon-Jun Chang [email protected] Yoon-Hee Kim [email protected] Yun-Hwan Kang [email protected] Myung-Hwan Choi [email protected] 1

Department of Food and Nutrition, Daegu University, Gyeonsan 38453, Korea

2

National Institute for Korean Medicine Development, Gyeonsan 38540, Korea

3

Hanbando, R&DB Center, Gyeonsan 38453, Korea

used for the production of SMCB-II. The SMCBs would be expected to contribute to an easy-to-carry, easy-to-consume, and high value-added health beverage for the modern people. Keywords Antibacterial  Antioxidant  Medicinal plants  Nitric oxide  Stick-type medicinal concentrated beverage

Introduction The main air pollutants have received growing attention as the key cause of respiratory illnesses in modern society. Respiratory system illnesses can also be caused by various bacteria. According to the Centers for Disease Control and Prevention, the most common cause of nosocomial pneumonia cases was Staphylococcus aureus between 1990 and 1992 in the United States (Emori and Gaynes, 1993). In addition, Corynebacterium diphtheriae is the main cause of diphtheria, a bacterial respiratory infection (Belsey et al., 1969); Streptococcus pyogenes infects the upper airway (nose, pharynx, larynx, etc.) and is the causative pathogen of pharyngitis, pneumonia, and acute respiratory distress syndrome (Stevens, 1992). Mycobacterium sp. is classified into tuberculous and non-tuberculous bacteria, where the latter is predominantly responsible for pulmonary diseases (Stout et al., 2016). A bronchial disease is caused when the bronchial mucosal cells are weakened by the common cold, fine particulate matter, or cigarette smoking, and the secondary infection