Appropriate Use of Progesterone to Prevent Preterm Birth: Approaches to Measurement for Driving Improvement

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FROM THE FIELD

Appropriate Use of Progesterone to Prevent Preterm Birth: Approaches to Measurement for Driving Improvement Priya Batra1  · Ashley Hirai2 · Sabrina Selk3 · Vanessa Lee2 · Michael Lu2 

© Springer Science+Business Media New York 2017

Abstract Introduction Despite strong evidence supporting the benefit of 17-alpha hydroxyprogesterone caproate (17P) in preventing recurrent preterm birth, this treatment still does not reach most eligible patients. This study sought to identify approaches to measuring the appropriate use of 17P, with the goal of helping health systems better monitor and improve the implementation of this intervention. Methods Semi-structured telephone interviews were used to gather data on measures for 17P use being developed and implemented by state team members participating in the Infant Mortality Collaborative Improvement and Innovation Network (IM CoIIN)—a national quality improvement initiative. Strengths and limitations of these measurement

Electronic Supplementary Material The online version of this article (doi:10.1007/s10995-016-2234-3) contains supplementary material, which is available to authorized users. * Priya Batra [email protected] Ashley Hirai [email protected] Sabrina Selk [email protected] Vanessa Lee [email protected] Michael Lu [email protected] 1

School of Medicine, Center for Healthy Communities, University of California, 900 University Avenue, Riverside, CA 92521, USA

2

Maternal and Child Health Bureau, Health Resources and Services Administration, Rockville, MD, USA

3

National Institute for Children’s Health Quality, Boston, MA, USA

approaches were described. Results Six approaches to measuring 17P use to prevent preterm birth were identified: practice-level data, population-based surveys, three measures employing insurance claims with or without linked birth certificate data, and revised birth certificates. Each measure had particular strengths and limitations. Practicelevel measures were useful in rapid-cycle improvement, but were not generalizable across sites. In contrast, population-based measures (i.e., surveys, claims) were useful for broad comparisons, but were limited in their timeliness, and in how accurately they identified candidates who were truly eligible for 17P. Additionally, such measures required complex data linkage and analytic capabilities. Discussion A variety of imperfect measures for the appropriate use of 17P are available. No “best” measure was identified—the optimal measurement option must fit the specific needs of a health agency. Better data infrastructure and harnessing information from integrated electronic health records could improve the quality of 17P use measurement for improvement efforts. Keywords Quality improvement · Measurement · Progesterone · Preterm birth

Significance What is known on this subject? 17-hydroxyprogesterone caproate (17P) has emerged as an obstetric intervention to reduce the risk of recurrent preterm birth—a health outcome that is associated with significant morbidity and health care costs. Despite