Attended Versus Unattended Automated Office Blood Pressure: A Systematic Review and Meta-analysis
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REVIEW
Attended Versus Unattended Automated Office Blood Pressure: A Systematic Review and Meta‑analysis Emmanuel A. Andreadis1 · Costas Thomopoulos2 · Charalampia V. Geladari1 · Vasilios Papademetriou3 Received: 3 June 2019 / Accepted: 2 July 2019 © Italian Society of Hypertension 2019
Abstract Introduction Automated office blood pressure (AOBP) has been proposed for blood pressure (BP) assessment in the office because it shows a strong association with the awake ambulatory BP. However, it remains unknown whether the presence or absence of an observer modulates AOBP readings. Aim To determine the difference between unattended and attended AOBP measurements through systematic review and meta-analysis. Methods We searched the PubMed and the Cochrane Collaboration Library and we screened the references’ list of relevant reports to identify potentially eligible articles. For included studies, quality was assessed by using the Quality Assessment for Diagnostic Accuracy Studies 2. The weighted pooled BP difference with 95% confidence interval (CI) between unattended and attended AOBP was estimated under the random effects model. Results Twelve studies (1762 subjects) were included. The systolic and diastolic BP difference between unattended and attended AOBP measurements was − 3.66 (− 6.58 to − 0.75) and − 1.67 (− 2.78 to − 0.55) mmHg, respectively. Heterogeneity across studies was high (I2 = 97,1% for systolic and I2 = 89% for diastolic BP, P
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