Behavioral Neuroscience of Attention Deficit Hyperactivity Disorder and Its Treatment

The Behavioral Neuroscience of Attention Deficit Hyperactivity Disorder reviews the latest discoveries in research of ADHD.  There is a strong emphasis on translational science, with preclinical approaches suggesting new directions for development of

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About this series Current Topics in Behavioral Neurosciences provides critical and comprehensive discussions of the most significant areas of behavioral neuroscience research, written by leading international authorities. Each volume offers an informative and contemporary account of its subject, making it an unrivalled reference source. Titles in this series are available in both print and electronic formats. With the development of new methodologies for brain imaging, genetic and genomic analyses, molecular engineering of mutant animals, novel routes for drug delivery, and sophisticated cross-species behavioral assessments, it is now possible to study behavior relevant to psychiatric and neurological diseases and disorders on the physiological level. The Behavioral Neurosciences series focuses on ‘‘translational medicine’’ and cutting-edge technologies. Preclinical and clinical trials for the development of new diagnostics and therapeutics as well as prevention efforts are covered whenever possible.

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Clare Stanford Rosemary Tannock l

Editors

Behavioral Neuroscience of Attention Deficit Hyperactivity Disorder and Its Treatment

Editors Dr. S. Clare Stanford Department of Neuroscience Physiology & Pharmacology University College London Gower Street WC1E 6BT London United Kingdom [email protected]

Dr. Rosemary Tannock Applied Psychology & Human Development The Ontario Institute for Studies in Education University of Toronto 252 Bloor Street West Toronto, Ontario M5S 1V6 Canada [email protected]

ISSN 1866-3370 e-ISSN 1866-3389 ISBN 978-3-642-24611-1 e-ISBN 978-3-642-24612-8 DOI 10.1007/978-3-642-24612-8 Springer Heidelberg Dordrecht London New York Library of Congress Control Number: 2011943172 # Springer-Verlag Berlin Heidelberg 2012 This work is subject to copyright. All rights are reserved, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilm or in any other way, and storage in data banks. Duplication of this publication or parts thereof is permitted only under the provisions of the German Copyright Law of September 9, 1965, in its current version, and permission for use must always be obtained from Springer. Violations are liable to prosecution under the German Copyright Law. The use of general descriptive names, registered names, trademarks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. Printed on acid-free paper Springer is part of Springer Science+Business Media (www.springer.com)

A Tribute to Terje Sagvolden (Feb 12, 1945 to Jan 12, 2011)

We dedicate this edited volume on Attention-Deficit Hyperactivity Disorder (ADHD) to Terje Sagvolden, a highly accomplished neuroscientist of international repute, a wonderful caring man, a kind considerate friend, and an inspiring researcher. His seminal work was to demons