Benzodiazepines II A Handbook. Basic Data, Analytical Methods, P
" ... this is an excellent compilation of data which should be on the bookshelves of all analysts interested in the benzodiazepines. It is to be hoped that, with the introduction of so many new ben zodiazepines, the author will quickly add these in a sec
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Benzodiazepines II A Handbook Basic Data, Analytical Methods, Pharmacokinetics and Comprehensive Literature With 183 Figures
Springer-Verlag Berlin Heidelberg New York London Paris Tokyo
Prof. Dr. rer. nat. Harald Schutz Diplom-Chemiker Institut fur Rechtsmedizin der lustus-Liebig-UniversiHit Frankfurter Strasse 58, D-6300 Giessen
ISBN-13: 978-3-642-74033-6 DOl: 10.1007/978-3-642-74031-2
e-ISBN-13: 978-3-642-74031-2
Library of Congress Cataloging-in-Publication Data. (Revised for vol. 2) Schutz, Harald, Dr. rer. nat. Benzodiazepines : a handbook. 1. Benzodiazepines. 1. Title. RM666.B42S38 1982615'.78 82-177936. This work is subject to copyright. All rights are reserved, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in other ways, and storage in data banks. Duplication of this publication or parts thereof is only permitted under the provisions of the German Copyright Law of September 9,1965, in its version of June 24, 1985, and a copyright fee must always be paid. Violations fall under the prosecution act of the German Copyright Law. © Springer-Verlag Berlin Heidelberg 1989
Softcover reprint of the hardcover 1st edition 1989 The use of registered names, trademarks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. Product Liability: The publisher can give no guarantee for information about drug dosage and application thereof contained in this book. In every individual case the respective user must check its accuracy by consulting other pharmaceutical literature.
2119/3140-543210 - Printed on acid-free paper
Dedicated to Dr. Dr. h.c. Leo Henryk Sternbach
Preface
" ... this is an excellent compilation of data which should be on the bookshelves of all analysts interested in the benzodiazepines. It is to be hoped that, with the introduction of so many new benzodiazepines, the author will quickly add these in a second edition" (A. C. Moffat in: Trends in Analytical Chemistry, 1983). This review, deputizing for many others, reflects the friendly reception enjoyed by the first volume of Benzodiazepines, which was published in 1982 and apparently closed a gap in the benzodiazepine literature. In the meantime, Benzodiazepines has established itself as a standard book, as evidenced by numerous letters and quotations. Suggestions were also soon made for a new edition in view of the unusually rapid development in the field of the benzodiazepines. It became quickly obvious, however, that it would not be sufficient to publish a revised second edition, but that a completely new second volume would be required for which, however, the successful previous format could be largely retained. The following considerations seem worth mentioning in connection with the preparation of Volume II: - To ensure continuity with Volume I as far as po
