Biochemical Pharmacology of Ethanol

A number of excellent symposia, reviews and monographs on the biology of ethanol have been published during the last decade. Al­ though it may appear that another such publication may be superflu­ ous, the subject of alcohol abuse is still open for furthe

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ADV ANCES IN EXPERIMENTAL MEDICINE AND BIOLOGY Editorial Board: Nathan Back

State University of New York at Buffalo

N. R. Di Luzio

Tulane University School of Medicine

Bernard Halpern

College de France and Institute of Immuno·Biology

Ephraim Katchalski

The Weizmann Institute of Science

David Kritchevsky

Wistar Institute

Abel Lajtha

New York State Research Institute for Neurochemistry and Drug Addiction

Rodolfo Paoletti

University of Milan

Recent Volumes in this Series Volume 46 PARENTERAL NUTRITION IN INFANCY AND CHILDHOOD Edited by Hans Henning Bode and Joseph B. Warshaw. 1974 Volume 47 CONTROLLED RELEASE OF BIOLOGICALLY ACTIVE AGENTS Edited by A. C. Tanquary and R. E. Lacey • 1974 Volume 48 PROTEIN-METAL INTERACTIONS Edited by Mendel Friedman. 1974 Volume 49 NUTRITION AND MALNUTRITION: Identification and Measurement Edited by Alexander F. Roche and Frank Falkner. 1974 Volume 50 ION.SELECTIVE MICROELECTRODES Edited by Herbert J. Berman and Normand C. Hebert. 1974 Volume 51 THE CELL SURFACE: Immunological and Chemical Approaches Edited by Barry D. Kahan and Ralph A. Reisfeld • 1974 Volume 52 HEPARIN: Structure, Function, and Clinical Implications Edited by Ralph A. Bradshaw and Stanford Wessler. 1975 Volume 53 CELL IMPAIRMENT IN AGING AND DEVELOPMENT Edited by Vincent J. Cristofalo and Emma Holeckova • 1975 Volume 54 BIOLOGICAL RHYTHMS AND ENDOCRINE FUNCTION Edited by Laurence W. Hedlund, John M. Franz, and Alexander D. Kenny • 1975 Volume 55 CONCANAVALIN A Edited by Tushar K. Chowdhury and A. Kurt Weiss. 1975 Volume 56 BIOCHEMICAL PHARMACOLOGY OF ETHANOL Edited by Edward Majchrowicz • 1975

BIOCHEMICAL PHARMACOLOGY OF ETHANOL

Edited by

Edward Majchrowicz Laboratory of Alcohol Research National Institute on Alcohol Abuse and Alcoholism Washington, D.C.

PLENUM PRESS • NEW YORK AND LONDON

Libnofy of CODI!; retl5 Calalol!;in l!; in Publi(,llion

0111

tthin entr,. under tille: Bio(hemical phumacolol!;,. of et hl nol. (Adnncet in experimental med icine Ind biolol!;Y ; Y.,56) " Proceedinl!;l of the Ame rican Chemical Society aymposi um ... he ld in Chic:al!;o, llIinoil, AUI UI" 1973. Includet bibliol!;rlphiet Ind index. 1. Alc:ohol - Ph,..iolol!;ical effect - Congrenel. 2. Alcohol mctaboli,m COnl!;reliea. I . Mljchrowkz, Edward. II. American Chemiui Society : III. Seri n. [ DNLM : I. Altohol, Eth yl - Pbannacodynamiu - Co ngrCSlU W I ADSS9 Y. 56 1913 / QV84 A506b 1913] QP981.A35B56 615'.782 75·8369 15BN 978-1-4684-753 1-9 l5BN 978-1-4684-7529-6 (elwo k) 0 01 10.1 007/978-1-4684-7529-6

Proceedin p of the American Chemical Society aymposi um On Biochemical Ph umacolol!Y of Ellii nol, held in Chical!;o, Illinois, Auguat,I973

=1975 Plenum Pre .., New York

Softcover reprint of the hardcover 1st edition 1975

A Divil ion of Plenum Publi, hinl!; Corporation 221 Wed 11th Street, New York.., N.Y. IOOll United Ki nl!;dom ed ition published b,. Plenum Pre... Londo n A Divition of Plenum Publishinl Com pln,.. Ltd. Davi, H OU K (4th Floo r ), 8 Serubl Lane, Hlflelden, Londo n, NW IO 6SE, Enl l. nd All rip lll