Bioinformatics Research and Applications 12th International Symposiu

This book constitutes the proceedings of the 12th International Symposium on Bioinformatics Research and Applications, ISBRA 2016, held in Minsk, Belarus, in June 2016. The 25 papers presented in this volume were carefully reviewed and selected from 77 su

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Anu Bourgeois · Pavel Skums Xiang Wan · Alex Zelikovsky (Eds.)

Bioinformatics Research and Applications 12th International Symposium, ISBRA 2016 Minsk, Belarus, June 5–8, 2016 Proceedings

123

Lecture Notes in Bioinformatics

9683

Subseries of Lecture Notes in Computer Science

LNBI Series Editors Sorin Istrail Brown University, Providence, RI, USA Pavel Pevzner University of California, San Diego, CA, USA Michael Waterman University of Southern California, Los Angeles, CA, USA

LNBI Editorial Board Søren Brunak Technical University of Denmark, Kongens Lyngby, Denmark Mikhail S. Gelfand IITP, Research and Training Center on Bioinformatics, Moscow, Russia Thomas Lengauer Max Planck Institute for Informatics, Saarbrücken, Germany Satoru Miyano University of Tokyo, Tokyo, Japan Eugene Myers Max Planck Institute of Molecular Cell Biology and Genetics, Dresden, Germany Marie-France Sagot Université Lyon 1, Villeurbanne, France David Sankoff University of Ottawa, Ottawa, Canada Ron Shamir Tel Aviv University, Ramat Aviv, Tel Aviv, Israel Terry Speed Walter and Eliza Hall Institute of Medical Research, Melbourne, VIC, Australia Martin Vingron Max Planck Institute for Molecular Genetics, Berlin, Germany W. Eric Wong University of Texas at Dallas, Richardson, TX, USA

More information about this series at http://www.springer.com/series/5381

Anu Bourgeois Pavel Skums Xiang Wan Alex Zelikovsky (Eds.) •



Bioinformatics Research and Applications 12th International Symposium, ISBRA 2016 Minsk, Belarus, June 5–8, 2016 Proceedings

123

Editors Anu Bourgeois Department of Computer Science Georgia State University Atlanta, GA USA

Xiang Wan Department of Computer Science Hong Kong Baptist University Kowloon Tong Hong Kong SAR

Pavel Skums Centre for Disease Control and Prevention Atlanta, GA USA

Alex Zelikovsky Georgia State University Atlanta, GA USA

ISSN 0302-9743 Lecture Notes in Bioinformatics ISBN 978-3-319-38781-9 DOI 10.1007/978-3-319-38782-6

ISSN 1611-3349

(electronic)

ISBN 978-3-319-38782-6

(eBook)

Library of Congress Control Number: 2016938416 LNCS Sublibrary: SL8 – Bioinformatics © Springer International Publishing Switzerland 2016 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. The publisher, the authors and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at