Biomaterials for Musculoskeletal Regeneration Concepts
This book covers the basics of the biomaterials science its applications to bone tissue engineering. The introductory section describes the most necessary concepts and techniques related to the cell and molecular biology with a particular focus on evaluat
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Bikramjit Basu
Biomaterials for Musculoskeletal Regeneration Concepts
Metallurgy Materials Engineering
Indian Institute of Metals Series Editor-in-chief Baldev Raj, National Institute of Advanced Studies, Bengaluru, Karnataka, India U. Kamachi Mudali, Indira Gandhi Centre for Atomic Research, Kalpakkam, Tamil Nadu, India
More information about this series at http://www.springer.com/series/15453
Bikramjit Basu
Biomaterials for Musculoskeletal Regeneration Concepts
123
Bikramjit Basu Indian Institute of Science Bangalore, Karnataka India
ISSN 2509-6400 Indian Institute of Metals Series ISBN 978-981-10-3058-1 DOI 10.1007/978-981-10-3059-8
ISSN 2509-6419
(electronic)
ISBN 978-981-10-3059-8
(eBook)
Library of Congress Control Number: 2016955926 © Springer Nature Singapore Pte Ltd. 2017 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. The publisher, the authors and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at the date of publication. Neither the publisher nor the authors or the editors give a warranty, express or implied, with respect to the material contained herein or for any errors or omissions that may have been made. Printed on acid-free paper This Springer imprint is published by Springer Nature The registered company is Springer Nature Singapore Pte Ltd. The registered company address is: 152 Beach Road, #22-06/08 Gateway East, Singapore 189721, Singapore
Dedicated to my wife, Pritha Basu and my son, Prithvijit Basu
Foreword
The last couple of decades has witnessed unprecedented growth in the fields of biomaterials and biomedical engineering. Researchers have taken significant steps to develop new biomaterials with a broad spectrum of physical and functional properties for skeletal and bone tissue engineering applications. These attempts were largely directed to recreate functional musculoskeletal systems with considerable potential to treat various types of irreversible damage in tissues that occur due to diseases such as Duchenne muscular dystrophy, spinal muscular atrophy, myopathy, and also bone diseases, such as osteoarthritis, osteoporosis, and osteomyelitis. Given the severity of prosthetic infection and worsening joint damage, regardless of the availability of antibiotics, many research programs have also focussed on developing antibact
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