Biosensors for Clinical Samples: Consideration and Approaches

The development of biosensors and bioassays has focused recently on small, easy to use in a decentralized and portable manner and low-cost analytical devices for sensing and quantitative determination of biomarkers. Biosensors provide numerous advantages

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mmunodiagnostic Technologies from Laboratory to Point-Of-Care Testing

Immunodiagnostic Technologies from Laboratory to Point-Of-Care Testing

Pankaj Suman • Pranjal Chandra Editors

Immunodiagnostic Technologies from Laboratory to Point-Of-Care Testing

Editors Pankaj Suman Animal Biotechnology Laboratory National Institute of Animal Biotechnology (NIAB) Hyderabad Hyderabad, Telangana, India

Pranjal Chandra School of Biochemical Engineering, Indian Institute of Technology Laboratory of Bio-Physio Sensors and Nano-bioengineering Varanasi, Uttar Pradesh, India

ISBN 978-981-15-5822-1 ISBN 978-981-15-5823-8 https://doi.org/10.1007/978-981-15-5823-8

(eBook)

# Springer Nature Singapore Pte Ltd. 2021 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. The publisher, the authors, and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at the date of publication. Neither the publisher nor the authors or the editors give a warranty, expressed or implied, with respect to the material contained herein or for any errors or omissions that may have been made. The publisher remains neutral with regard to jurisdictional claims in published maps and institutional affiliations. This Springer imprint is published by the registered company Springer Nature Singapore Pte Ltd. The registered company address is: 152 Beach Road, #21-01/04 Gateway East, Singapore 189721, Singapore

Contents

Biosensors for Clinical Samples: Consideration and Approaches . . . . . . Mihaela Tertis, Oana Hosu, Anca Florea, and Cecilia Cristea

1

Immunodiagnosis by Electrochemical Multiplexing in Clinical Samples . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . S. Campuzano, P. Yáñez-Sedeño, and José M. Pingarrón

33

Principle and Applications of Immunodiagnostics Using Radioisotope as Tracers . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Shishu Kant Suman, Rohit Sharma, and Chandan Kumar

61

Redox Cycling Technologies for Point-of-Care Immunodiagnostics in Various Matrices . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Gorachand Dutta, Despina Moschou, and Riddhipratim Mandal

75

Next-Generation Immunosensing Technologies Based on Nano-Bio-Engineered Paper Matrices . . . . . . . . . . . . . . . . . .