Bone Pathology
Bone Pathology is the second edition of the book, A Compendium of Skeletal Pathology that published 10 years ago. Similar to the prior edition, this book complements standard pathology texts and blends new but relatively established information on the mol
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Jasvir S. Khurana Editor
Bone Pathology Second Edition
Editor Jasvir S. Khurana Temple University Hospital 3401 North Broad Street Philadelphia PA 19140 USA [email protected]
ISBN: 978-1-58829-766-2 e-ISBN: 978-1-59745-347-9 DOI: 10.1007/978-1-59745-347-9 Springer Dordrecht Heidelberg London New York Library of Congress Control Number: 2008939906 © Humana Press, a part of Springer Science+Business Media, LLC 2009 All rights reserved. This work may not be translated or copied in whole or in part without the written permission of the publisher (Humana Press, c/o Springer Science+Business Media, LLC, 233 Spring Street, New York, NY 10013, USA), except for brief excerpts in connection with reviews or scholarly analysis. Use in connection with any form of information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed is forbidden. The use in this publication of trade names, trademarks, service marks, and similar terms, even if they are not identified as such, is not to be taken as an expression of opinion as to whether or not they are subject to proprietary rights. While the advice and information in this book are believed to be true and accurate at the date of going to press, neither the authors nor the editors nor the publisher can accept any legal responsibility for any errors or omissions that may be made. The publisher makes no warranty, express or implied, with respect to the material contained herein. Printed on acid-free paper Springer is part of Springer Science+Business Media (www.springer.com)
Preface
This is the second edition of the book A Compendium of Skeletal Pathology published 8 years ago. Similar to the prior edition, the goal of this book is to form a blend between new information and serve as a bench-side companion to the surgical pathologist. In this book, established and tested information is emphasized over the new but untried. In the same spirit, and in order to promote brevity, referencing has been kept to a minimum or eliminated altogether in many chapters. Some chapters however, where there is considerable new information (such as anatomy and molecular biology), are more completely referenced. In this context, I am reminded of Sir Hutchinson’s book of clinical signs and symptoms, which begins “Before handing the cup of knowledge to the youth, wait for the froth to settle.” There are several changes to this edition. Since there have been several new advances in our understanding of the molecular biology of bone, the first chapter has been extensively rewritten. A new section on the molecular diagnosis of softtissue sarcomas and a new section on biomechanics have been included in this edition. An entirely new chapter on soft-tissue tumors has been added, since there is a close relationship between the soft tissue and bone pathology; and because pathologists, surgeons, and radiologists with an interest in bone often have to deal with soft-tissue tumors as well. The chapter on skeletal dysplasia is up
