Book Reviews
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Book Reviews
Hypertension: Methods and Protocols
Genomics: Applications in Human Biology
Jerome P. Fennell and Andrew H. Baker (Editors) Humana Press, Totowa, NJ, USA; 2005; ISBN: 1-58829-323-8; 520 pp.; US$135.00
Sandy B. Primrose, Richard M. Twyman Blackwell Publishing, Malden, MA, USA; 2004; ISBN: 1-4051-0819-3; 204 pp.; Hardback UK £29.99/US$62.95 Genomics has revolutionised the theory and practice of medicine. The impact of genomics on diagnostics, disease management and risk assessment has been felt by the medical community and the public in general. Indeed, the era of personalised medicine has come upon us, and with it, a revolution in every aspect of medicine and drug development. ‘Genomics: Applications in Human Biology’ is a refreshing, light and insightful examination of the emerging field of genomics and its applications in human biology, medicine and drug development. The book is written for advanced undergraduates, but its coverage can be regarded as a wonderful resource for practising clinicians, public health officials and students searching for ‘real world’ applications of genomics. Primrose and Twyman navigate complex subjects effortlessly and make superb use of graphics and tabular presentations to emphasise important points throughout the individual chapters. The book includes a well-organised compilation of technological developments and their applications, giving broad treatment to varying subjects in the areas of infectious disease, genetic disease, cancer, biopharmaceuticals, new chemical entities and gene and cell-based therapies. The book achieves an excellent balance of scientific breadth and depth and provides an uplifting perspective into ethical considerations. The use of boxed text and highlights are excellent aids, which, coupled with easy flow and smooth transitions, provide a seamless and effective learning tool for the reader. The conspicuous absence of coloured illustrations is at times disappointing, and future editions of the book should correct the few typographical errors. That being said, the entire book can easily be read in a couple of sittings, quite an accomplishment for a subject that requires adequate treatment. All together, the book addresses complex subjects with clarity and provides insightful views about how genomics will shape our views of the world. The book serves as an excellent introduction for the novice and a valuable resource for the advanced reader. I expect that this edition will earn a place in many collections throughout the world. Kenneth S. Ramos University of Louisville Health Sciences Center Louisville, KY40292, USA
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Historically, hypertension research was the realm of physiologists and, latterly, biochemists. In the past 20 years, however, molecular biology has relentlessly influenced the way in which hypertension research is carried out. Acquiring these new techniques and other ‘cutting edge’ technologies has been essential to maintaining research momentum, but it is often not a straightforward process. This book attempts to address this, wit
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