BRAF Targets in Melanoma Biological Mechanisms, Resistance, and Drug
This volume contains a collection of writings from the leaders in the fields of Molecular Biology and Melanoma Research which will begin to tell the ever-expanding story of the most recent findings, discoveries, and potential of BRAF-directed targets in m
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Series Editor Beverly A. Teicher Bethesda, Maryland, USA
Cancer Drug Discovery and Development, the Springer series headed by Beverly A. Teicher, is the definitive book series in cancer research and oncology. Volumes cover the process of drug discovery, preclinical models in cancer research, specific drug target groups, and experimental and approved therapeutic agents. The volumes are current and timely, anticipating areas where experimental agents are reaching FDA approval. Each volume is edited by an expert in the field covered, and chapters are authored by renowned scientists and physicians in their fields of interest. For more information about this series, go to http://www.springer.com/series/7625
Ryan J. Sullivan Editor
BRAF Targets in Melanoma Biological Mechanisms, Resistance, and Drug Discovery
Editor Ryan J. Sullivan Center for Melanoma Massachusetts General Hospital Cancer Center Boston Massachusetts USA
ISSN 2196-9906 ISSN 2196-9914 (electronic) ISBN 978-1-4939-2142-3 ISBN 978-1-4939-2143-0 (eBook) DOI 10.1007/978-1-4939-2143-0 Springer New York Heidelberg Dordrecht London Library of Congress Control Number: 2014955080 © Springer Science+Business Media New York 2015 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. Exempted from this legal reservation are brief excerpts in connection with reviews or scholarly analysis or material supplied specifically for the purpose of being entered and executed on a computer system, for exclusive use by the purchaser of the work. Duplication of this publication or parts thereof is permitted only under the provisions of the Copyright Law of the Publisher’s location, in its current version, and permission for use must always be obtained from Springer. Permissions for use may be obtained through RightsLink at the Copyright Clearance Center. Violations are liable to prosecution under the respective Copyright Law. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. While the advice and information in this book are believed to be true and accurate at the date of publication, neither the authors nor the editors nor the publisher can accept any legal responsibility for any errors or omissions that may be made. The publisher makes no warranty, express or implied, with respect to the material contained herein. Printed on acid-free paper Springer is part of Springer Science+Business Media (www.springer.com)
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