Bronchiectasis The EMBARC Manual

This book presents state of the art knowledge and practice in the rapidly developing field of bronchiectasis not due to cystic fibrosis (referred to below simply as bronchiectasis). The focus is especially on diagnosis and existing and emerging therapies,

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Bronchiectasis The EMBARC Manual

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Bronchiectasis

James Chalmers  •  Eva Polverino Stefano Aliberti Editors

Bronchiectasis The EMBARC Manual

Editors James Chalmers College of Medicine University of Dundee Dundee United Kingdom Stefano Aliberti Department of Pathophysiology and Transplantation, University of Milan Internal Medicine Department Respiratory Unit and Cystic Fibrosis Adult Center, Fondazione IRCCS Ca’ Granda Ospedale Maggiore Policlinico Milan Italy

Eva Polverino Hospital Vall D’Hebron Vall D’Hebron Research Institute (VHIR) Respiratory Disease Department Barcelona Spain

ISBN 978-3-319-61451-9    ISBN 978-3-319-61452-6 (eBook) https://doi.org/10.1007/978-3-319-61452-6 Library of Congress Control Number: 2017960813 © Springer International Publishing AG 2018 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. The publisher, the authors and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at the date of publication. Neither the publisher nor the authors or the editors give a warranty, express or implied, with respect to the material contained herein or for any errors or omissions that may have been made. The publisher remains neutral with regard to jurisdictional claims in published maps and institutional affiliations. Printed on acid-free paper This Springer imprint is published by Springer Nature The registered company is Springer International Publishing AG The registered company address is: Gewerbestrasse 11, 6330 Cham, Switzerland

Preface

In the long history of humankind (and animal kind, too) those who learned to collaborate and improvise most effectively have prevailed.—Charles Darwin

The European Multicentre Bronchiectasis Audit and Research Collaboration (EMBARC) was formed in 2012 to stimulate clinical and scientific advances in the field of bronchiectasis. The group, representing dedicated clinicians in more than 30 countries, was then established by the European Respiratory Society, the world’s largest organisation for respiratory professionals, as a clinical research collaboration initiative (www.bronchiectasis.eu). In the 5 years since it was formed, EMBARC has made an important contribution to raising the profile of bronchiectasis within the respiratory community. We have established a European Bronchiectasis Registry, the first inte