Calcinosis as a complication of juvenile dermatomyositis (JDM)
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POSTER PRESENTATION
Open Access
Calcinosis as a complication of juvenile dermatomyositis (JDM) Malagón Clara*, Yépez Ricardo, Contreras Luz From 18th Pediatric Rheumatology European Society (PReS) Congress Bruges, Belgium. 14-18 September 2011 Background Calcinosis is a common complication of JDM. It may varies on extension and severity. May cause mechanical and aesthetic complications and predispose to infections. Aim To evaluate the frequency and features of calcinosis in a cohort of patients with JDM and identify if there are risk factors. Methods Retrospective descriptive study in 3 pediatric rheumatology centers in Bogota during a period of 20 years. Two groups were identified according to the presence or absence of clinical and radiological signs of calcinosis after a minimum of 2 years of follow up. Results 17/42 developed calcinosis associated with earlier onset of the disease, male predominance and chronic. Calcium Table GROUP
With calcinosis
Without calcinosis
Number
17
25
Sex distribution (Male:female)
1.83:1
1:3.16
0,008
7,08(2-16)
0,633
Age of onset (average of years) 6,29(1,5-12)
deposits were classified as: superficial nodular, deep nodular, mass, linear or mixed deposits and calcinosis universalis. 80% had two or more types of deposits. The anatomical areas more frequently affected were the thighs and forearms. Complications included: drainage, chronic ulcers, mass effect, mechanical blockage of the joints and infections. Severe calcinosis was also associated with significant muscle atrophy loss and lipodystrophy.
Conclusion Calcinosis is common and severe of JDM. It leads to various complications and treatment response is poor. Early diagnosis and proper treatment may reduce the frequency of this complication. Published: 14 September 2011
doi:10.1186/1546-0096-9-S1-P55 Cite this article as: Clara et al.: Calcinosis as a complication of juvenile dermatomyositis (JDM). Pediatric Rheumatology 2011 9(Suppl 1):P55.
Pvalue
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Delayed diagnosis (>6months)
6/17
35%
5/25
20%
0,268
Monocyclic Policiclic
1/17 3/17
6% 18%
12/25 3/25
48% 12%
0,004 0,608
• Convenient online submission
Chronic
14/17
82%
7/25
28%
0,001
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• Thorough peer review
• Immediate publication on acceptance • Inclusion in PubMed, CAS, Scopus and Google Scholar • Research which is freely available for redistribution
* Correspondence: [email protected] Pediatric Rheumatology fellowship program, Faculty of Medicine, Universidad el Bosque, Bogotá, Colombia
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© 2011 Clara et al; licensee BioMed Central Ltd. This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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