Calcium carbonate
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Milk-alkali syndrome: case report A 47-year-old woman developed milk-alkali syndrome during treatment with calcium carbonate-containing preparations [duration of therapy to reaction onset and therapeutic indications not stated]. The woman, who had Down’s syndrome and a history of hypothyroidism, was receiving two calcium preparations three times a day, one of these preparations contained calcium carbonate 500mg and vitamin D and the other contained calcium carbonate 500mg; concomitant medications included raloxifene, risperidol [sic], alendronic acid and levothyroxine sodium. She presented at an emergency department with a history of abdominal pain, lethargy, constipation and loss of appetite. Laboratory investigations at admission revealed the following: sodium 148 mmol/L, potassium 3.3 mmol/L, bicarbonate 33 mmol/L, blood urea nitrogen 25 mg/dL, creatinine 4.1 mg/dL, glucose 79 mg/dL, intact parathyroid hormone 8.9 pg/dL and calcium > 16.5 mg/dL. The woman received IV fluids and furosemide for hypercalcaemia secondary to milk-alkali syndrome. Her serum calcium level returned to normal in 2 days and her renal function normalised. Shah BK, et al. Modern milk alkali syndrome - a preventable serious condition. New Zealand Medical Journal 120: 65-67, No. 1262, 21 Sep 2007 801083163 USA
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Reactions 27 Oct 2007 No. 1175
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