Alfacalcidol/calcium carbonate
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Alfacalcidol/calcium carbonate Metastatic pulmonary calcification: case report A 66-year-old man developed metastatic pulmonary calcification during treatment with alfacalcidol and calcium carbonate [therapeutic indications not stated]. The man, who was on haemodialysis from past 35 years, presented due to severe multi-joint pain and contractures. He had a history of bilateral carpal tunnel syndrome. He had been receiving alfacalcidol 0.25 µg/day and calcium carbonate 3 g/day [routes not stated]. Laboratory investigations revealed hypercalcaemia, hyperphosphataemia and hyperβ2-microglobulinaemia. A CT scan demonstrated diffuse bilateral lung centrilobular ground-glass opacity and a mass near the coxae and glenohumeral joints. Based on the clinical picture, metastatic pulmonary calcification [durations of treatments to reaction onset and outcome not stated] and dialysis-related amyloidosis were diagnosed. Author comment: "In this case, we considered the cause of [metastatic pulmonary calcification] to be alfacalcidol, calcium carbonate, and long-term hemodialysis." Haji S, et al. Multijoint pain and pulmonary calcification with long-term hemodialysis. Internal Medicine 57: 3063-3064, No. 20, 15 Oct 2018. Available 803438525 from: URL: http://doi.org/10.2169/internalmedicine.0443-17 - Japan
0114-9954/19/1782-0001/$14.95 Adis © 2019 Springer Nature Switzerland AG. All rights reserved
Reactions 7 Dec 2019 No. 1782
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