Calcium signalling Approaches and Findings in the Heart and Blood

The book combines general concepts and methods to investigate calcium signalling in cells ranging from molecular biology approaches to manipulation of calcium in living cells.The focus within these methods in on the broad range of fluorescence imaging tec

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Lars Kaestner

Calcium signalling Approaches and Findings in the Heart and Blood

With 96 figures

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Dr. Lars Kaestner Universität des Saarlandes Institut für Molekulare Zellbiologie

ISBN-13 978-3-642-34616-3 DOI 10.1007/978-3-642-34617-0

ISBN 978-3-642-34617-0 (eBook)

Die Deutsche Nationalbibliothek verzeichnet diese Publikation in der Deutschen Nationalbibliografie; detaillierte bibliografische Daten sind im Internet über http://dnb.d-nb.de abrufbar. Springer Medizin © Springer-Verlag Berlin Heidelberg 2013 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. Exempted from this legal reservation are brief excerpts in connection with reviews or scholarly analysis or material supplied specifically for the purpose of being entered and executed on a computer system, for exclusive use by the purchaser of the work. Duplication of this publication or parts thereof is permitted only under the provisions of the Copyright Law of the Publisher’s location, in its current version, and permission for use must always be obtained from Springer. Permissions for use may be obtained through RightsLink at the Copyright Clearance Center. Violations are liable to prosecution under the respective Copyright Law. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. While the advice and information in this book are believed to be true and accurate at the date of publication, neither the authors nor the editors nor the publisher can accept any legal responsibility for any errors or omissions that may be made. The publisher makes no warranty, express or implied, with respect to the material contained herein.

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Foreword This book is a habilitation treatise. I aimed to both fulfil the formal requirements of the habilitation treatise as defined in the habilitation regulation of the Medical Faculty at Saarland University and provide a resource for colleagues, students and all that are interested in calcium signalling and/or optical imaging methods to record it. As such, I hope this booklet is more than a file in academic qualification, and that it might also serve as a useful tool whenever the universal messenger calcium crosses the track. The biological examples are recruited from two major fields, cellular cardiology and red cell research. I