Calorie Restriction, Aging and Longevity
Food or calorie restriction has been shown in many short-lived animals and the rhesus monkey to prolong life-span. Life-long nutrition studies are not possible in humans because of their long survival. Studies over two to six years in healthy adult humans
- PDF / 5,110,331 Bytes
- 327 Pages / 439.37 x 666.142 pts Page_size
- 31 Downloads / 187 Views
Arthur V. Everitt · Suresh I.S. Rattan · David G. Le Couteur · Rafael de Cabo Editors
Calorie Restriction, Aging and Longevity
123
Editors Arthur V. Everitt CERA C22, The University of Sydney, Sydney 2006 Australia [email protected] Suresh I.S. Rattan University of Aarhus 8000 Aarhus Denmark [email protected]
David G. Le Couteur CERA C22, The University of Sydney, Sydney 2006 Australia [email protected] Rafael de Cabo National Institute of Health National Institute on Aging Gerontology Research Center Baltimore MD 21224 USA [email protected]
ISBN 978-90-481-8555-9 e-ISBN 978-90-481-8556-6 DOI 10.1007/978-90-481-8556-6 Springer Dordrecht Heidelberg London New York Library of Congress Control Number: 2010922314 © Springer Science+Business Media B.V. 2010 No part of this work may be reproduced, stored in a retrieval system, or transmitted in any form or by any means, electronic, mechanical, photocopying, microfilming, recording or otherwise, without written permission from the Publisher, with the exception of any material supplied specifically for the purpose of being entered and executed on a computer system, for exclusive use by the purchaser of the work. Printed on acid-free paper Springer is part of Springer Science+Business Media (www.springer.com)
To my wife, Joyce, with love, and my son Michael, my daughter Sue, and their families Wishing everyone healthy, happy and long lives Arthur
Preface
Food or calorie restriction has been shown in many short-lived animals and the rhesus monkey to prolong life-span. Life-long nutrition studies are not possible in humans because of their long survival. Studies over 2–6 years in healthy adult humans have, however, shown that a 20% reduction in food or calorie intake slows many indices of normal and disease-related aging. Thus, it is widely believed that long-term reduction in calorie or food intake will delay the onset of age-related diseases such as heart disease, diabetes and cancer, and so prolong life. Over the last 20 or more years there has been a progressive rise in food intake in many countries of the world, accompanied by a rising incidence of overweight and obesity. Thus our increasing food and calorie intake has been linked to the rising incidence of cardiovascular disease and diabetes in early adult life. It is accepted that overeating, accompanied by reduced physical exercise, will lead to more age-related diseases and shortening of life-span. What can be done? Put simply, the answer is to reduce our calorie intake, improve our diet, and exercise more. But calorie restriction is extremely difficult to maintain for long periods. How then can we solve this problem? This book provides the latest information on the beneficial effects of calorie restriction on health and life-span and brings us closer to an understanding at the molecular, cellular and whole organism level of the way forward. Sydney, Australia Aarhus, Denmark Sydney, Australia Baltimore, Maryland, USA
Arthur V. Everitt Suresh I.S. Rattan David G. Le Couteur Rafael
Data Loading...
