Can cardiac MRI be the index metric for risk stratification in dilated cardiomyopathy; the impact of an LV mid-myocardia

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POSTER PRESENTATION

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Can cardiac MRI be the index metric for risk stratification in dilated cardiomyopathy; the impact of an LV mid-myocardial stripe on subsequent risk of LVAD, transplantation and death Jose Venero*, Mark Doyle, Srinivas Murali, Diane A Vido, Vikas K Rathi, Saundra Grant, June Yamrozik, Ronald B Williams, Raymond Benza, George Sokos, Peter Olson, Robert W Biederman From 15th Annual SCMR Scientific Sessions Orlando, FL, USA. 2-5 February 2012 Summary The mid-wall intramyocardial ‘stripe’ is now shown to be robust in its prediction of subsequent need for LVAD and/or transplantion and death out to 12 months following index CMR exam. Background Patients with newly diagnosed dilated cardiomyopathy (DCM) and advanced heart failure have a very high morbidity and mortality with an unpredictable clinical course. We investigated the role of CMR via LGE (late gadolinium enhancement) in this cohort of high-risk patients. Hypothesis Utilizing cardiovascular MRI (CMR), we assessed the prognostic value of LGE in primary dilated DCM patients referred for possible transplantation/ LVAD consideration. Methods Over 49 consecutive months, 61 consecutive DCM pts were referred for standard 3D CMR (1.5T,GE) to interrogate the LV pattern, distribution and extent of LGE (MultiHance, Princeton, NJ). Inclusion criteria for a primary non-ischemic dilated DCM and EF