Canakinumab

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Thrombocytopenia: case report In a study aimed to investigate the efficacy and safety of anti-Interleukin-1 agent in paediatric patients, a patient [sex and exact age not stated] was described, who developed thrombocytopenia, while receiving canakinumab for familial mediterranean fever (FMF). The patient, who had FMF, started receiving anti-interleukin-1 therapy with canakinumab [dosage and routes not stated]. However, the patient developed thrombocytopenia secondary to canakinumab [duration of treatment to reaction onset not stated]. Canakinumab was temporarily discontinued resulting in resolution of thrombocytopenia. Sag E, et al. Anti-IL1 treatment in colchicine resistant pediatric fmf patients-real life data from the helios registry. Annals of the Rheumatic Diseases 79 (Suppl.): 179-180 803516031 abstr. OP0288, Jun 2020. Available from: URL: https://ard.bmj.com/content/annrheumdis/79/Suppl_1/179.1.full.pdf [abstract]

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Reactions 21 Nov 2020 No. 1831