Cancer and Inflammation
How are cancer and inflammation interrelated mechanistically and clinically? Though extensive literature exists on the topic "Cancer and Inflammation", there are relatively few texts that have truly integrated the two in spite of the many common mechanism
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Series Editor Prof. Dr. Michael J. Parnham Senior Scientific Advisor PUVA dd Prilaz baruna Filipovica 25 10000 Zagreb Croatia Advisory Board G. Z. Feuerstein (Merck Research Laboratories, West Point, PA, USA) M. Pairet (Boehringer Ingelheim Pharma KG, Biberach a. d. Riss, Germany) W. van Eden (Universiteit Utrecht, Utrecht, The Netherlands)
Forthcoming titles: Antirheumatic Therapy: Adions and Dutcomes, R.D. Day, D.E. Furst, P.L. van Riel, B. Bresnihan (Editors), 2004 Antibiotics as Anti-inflammatory and Immunomodulatory Agents,
B.K. Rubin, J. Tamaoki (Editors), 2004 Bone Morphogenetic Proteins: Bone Regeneration and Beyond,
S. Vukicevic, K.T. Sampath (Editors), 2004
(Already published titles see last page.)
Cancer and Inflammation
Douglas W. Morgan Ulf J. Forssmann Marian T. Nakada Editors
Springer Basel AG
Editors Douglas W. Morgan TAP Pharmaceuticals 675 North Field Dr. Lake Forest, IL 60045 USA
Ulf J. Forssmann I PF PharmaCeuticals Feodor-Lynen-Strasse 31 30625 Hannover Germany
Marian T. Nakada Oncology Research Centocor 200 Great Valley Parkway Malvern, PA 19355 USA
A CIP catalogue record for this book is available from the Library of Congress, Washington D.C., USA
Bibliographic information published by Die Deutsche Bibliothek Die Deutsche Bibliothek lists this publication in the Deutsche Nationalbibliografie; detailed bibliographic data is available in the internet at http://dnb.ddb.de
The publisher and editor can give no guarantee for the information on drug dosage and administration contained in this publication. The respective user must check its accuracy by consulting other sources of reference in each individual case. The use of registered names, trademarks etc. in this publication, even if not identilied as such, does not imply that they are exempt from the relevant protective laws and regulations or Iree for general use.
ISBN 978-3-0348-9600-9 ISBN 978-3-0348-7861-6 (eBook) DOI 10.1007/978-3-0348-7861-6 This work is subject to copyright. AII rights are reserved, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, re-use of illustrations, recitation, broadcasting, reproduction on microfilms or in other ways, and storage in data banks. For any kind 01 use, permission of the copyright owner must be obtained.
© 2004 Springer Basel AG Originally published by Birkhăuser Verlag, Basel - Boston - Berlin in 2004 Softcover reprint of the hardcover 1 st edition 2004 Cover design: Markus Etterich, Basel Cover illustration: CD68-positive macrophages (red) are observed in close proximity to CD31-positive endothelial cells (black) using double immunohistochemical techniques in a representative area of a human colon carcinoma. AII nuclei (blue) have been counterstained with hematoxylin. Mags are as follows: 40x objective, total mag 600x, if use a bar size of 1.5 cm, then bar = 25 microns. We like to thank Danielle Lawrence and Dr. Michael R. D'Andrea of Johnson & Johnson Pharmaceutical Research & Development, Spring House, PA, for their contribut
