Cardiorenal Syndrome in Heart Failure

This comprehensive manual reviews the management of cardiorenal syndrome in heart failure. Chapters are structured in a practically applicable and easy-to-follow format with realistic case vignettes and key clinical management questions and answers, follo

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Cardiorenal Syndrome in Heart Failure

W. H. Wilson Tang Frederik H. Verbrugge  •  Wilfried Mullens Editors

Cardiorenal Syndrome in Heart Failure

Editors W. H. Wilson Tang Department of Cardiovascular Medicine Cleveland Clinic Cleveland, OH USA

Frederik H. Verbrugge Department of Internal Medicine UZ Leuven Leuven Belgium

Wilfried Mullens Ziekenhuis Oost-Limburg Genk University Hasselt Genk Belgium

ISBN 978-3-030-21032-8    ISBN 978-3-030-21033-5 (eBook) https://doi.org/10.1007/978-3-030-21033-5 © Springer Nature Switzerland AG 2020 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. The publisher, the authors, and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at the date of publication. Neither the publisher nor the authors or the editors give a warranty, expressed or implied, with respect to the material contained herein or for any errors or omissions that may have been made. The publisher remains neutral with regard to jurisdictional claims in published maps and institutional affiliations. This Springer imprint is published by the registered company Springer Nature Switzerland AG The registered company address is: Gewerbestrasse 11, 6330 Cham, Switzerland

Foreword

Heart failure continues to be a major medical problem across the globe. In the United States (US), it is the most common reason for patients to be hospitalized. Hospital cases of heart failure with preserved ejection fraction (HFpEF) are increasing in the US, while hospitalization for heart failure with a reduced ejection fraction (HFrEF) may be decreasing. Both conditions often present with fluid overload, pulmonary congestion, edema, and some renal function impairment. Most physicians know that aggressive diuretic therapy or other means of reducing excessive circulating volume can at times lead to worsening renal function and even acute kidney injury. When this occurs in the setting of acute decompensated heart failure, outcomes can be poor, and management can be challenging. This important new book brings together the clinician-scientists that have been actively studying the “cardio-renal syndrome” at various universities around the world. The authors know each other well and have been at the “front lines” in various laboratories trying to better understand what is really happening and how