The Breathless Heart Apneas in Heart Failure
This book systematically focuses on central sleep apneas, analyzing their relationship especially with heart failure and discussing recent research results and emerging treatment strategies based on feedback modulation. The opening chapters present histor
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The Breathless Heart Apneas in Heart Failure
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The Breathless Heart
Michele Emdin • Alberto Giannoni Claudio Passino Editors
The Breathless Heart Apneas in Heart Failure
Editors Michele Emdin Institute of Life Sciences Scuola Superiore Sant’Anna and Fondazione Toscana Gabriele Monasterio Pisa Italy
Claudio Passino Institute of Life Sciences Scuola Superiore Sant’Anna and Fondazione Toscana Gabriele Monasterio Pisa Italy
Alberto Giannoni Fondazione Toscana Gabrielle Monasterio Pisa Italy
ISBN 978-3-319-26352-6 ISBN 978-3-319-26354-0 DOI 10.1007/978-3-319-26354-0
(eBook)
Library of Congress Control Number: 2016959210 © Springer International Publishing Switzerland 2017 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. The publisher, the authors and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at the date of publication. Neither the publisher nor the authors or the editors give a warranty, express or implied, with respect to the material contained herein or for any errors or omissions that may have been made. Printed on acid-free paper This Springer imprint is published by Springer Nature The registered company is Springer International Publishing AG The registered company is Gewerbestrasse 11, 6330 Cham, Switzerland
Preface
Heart failure is a major cause of hospitalization and mortality, despite recent advancements in diagnosis and treatment. The search for hidden pathophysiological triggers of disease evolution and potential targets of therapy has rediscovered an old, forgotten feature of the heart failure syndrome: apnea. Apneas may present themselves either as a sign or a symptom in the individual patient, but are often overlooked by clinicians, though they are both a marker of severity and a mediator of risk. Apneas are invariably associated with cyclic hyperpneas both in the asleep and in the awake subject with heart failure, possibly as an initial compensatory response. Apnea/hyperpnea phenomena oblige the clinician to reevaluate the physiology of respiration and cardiovascular function. However, is there still place for physiology in the decision-making for patients with cardiovascular diseases in the era of imaging, genetics, and molecular biology? The answer is in the affirmative, as demonstrated by the clinical value of periodic breathing/Ch
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