Celiac Disease and the Liver
Liver inflammation in celiac disease (CeD) is not an uncommon phenomenon, as up to 10% of patients develop elevated transaminases. In most cases, the transaminases will normalize with a gluten-free diet (GFD). However, up to 2% of these patients will be d
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Diagnosis and Management of Gluten-Associated Disorders
Guy A. Weiss Editor
Diagnosis and Management of Gluten-Associated Disorders A Clinical Casebook
Editor
Guy A. Weiss David Geffen School of Medicine at UCLA University of California Los Angeles (UCLA) Celiac Disease Program Los Angeles, CA USA
ISBN 978-3-030-56721-7 ISBN 978-3-030-56722-4 (eBook) https://doi.org/10.1007/978-3-030-56722-4 © Springer Nature Switzerland AG 2021 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. The publisher, the authors and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at the date of publication. Neither the publisher nor the authors or the editors give a warranty, expressed or implied, with respect to the material contained herein or for any errors or omissions that may have been made. The publisher remains neutral with regard to jurisdictional claims in published maps and institutional affiliations. This Springer imprint is published by the registered company Springer Nature Switzerland AG The registered company address is: Gewerbestrasse 11, 6330 Cham, Switzerland
Preface
You are the place where language fails and I am the translator of no language –Morani Kornberg, Dear Darwish The field of gluten-associated disorders (GADs), or gluten- related disorders, has grown tremendously in recent years. These disorders represent a spectrum of immune-mediated reactions to wheat or gluten, once believed to be rare, but currently affecting approximately 5% of the US population. Gluten is present in wheat, rye, and barley and has viscoelastic properties, helps dough rise, and adds flavor. For these reasons, it is widely used in different food products (including non-cereal), leading to an increase in the total amount of gluten in a typical western diet. Based on pathogenesis, these disorders may be classified into three categories. The first, GADs of autoimmune origin, includes celiac disease (CeD), dermatitis herpetiformis (DH), and gluten ataxia (GA). The second, disorders of allergic origin, includes wheat allergy (WA) and eosinophilic gastroenteritis (EGE). The last group is comprised of conditions that are neither of autoimmune nor allergic origin, including non- celiac gluten sensitivity (NCGS), or non-celiac wheat sensitivity, and fructan intolerance (FI). Each dis
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