Cell Cycle Control
Leafing through a journal of biology will almost certainly turn up several arti cles on some aspect of the eukaryotic cell division cycle. The progress in un derstanding the modus operandi of the cell cycle machinery and its central role in controlling
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Springer-Verlag Berlin Heidelberg GmbH
Michele Pagano (Ed.)
Cell Cycle Control
With 17 Figures
Springer
Dr. Michele Pagano New York University School of Medicine Department of Pathology, MSB 548 550 First Avenue New York, NY 10016 USA
ISBN 978-3-662-21695-8 DOI 10.1007/978-3-540-69686-5
ISBN 978-3-540-69686-5 (eBook)
Library of Congress Cataloging-in-Publication Data CeH cycle controVMichele Pagano, ed. p. cm. -(Results and problems in ceH differentiation; 22) Includes bibliographical references and index. ISBN 3-540-64031-2 1. CeH cycle. 2. CeHular control mechanisms. 1. Pagano, M. (Michele), 1961-. II. Series. QH607.R4 voI. 22 [QH605] 571.8'35 s-dc21 [571.8'44] 98-10581
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© Springer-Verlag Berlin Heidelberg 1998 Originally published by Springer-Verlag Berlin Heidelberg New York in 1998 Softcover reprint ofthe hardcover lst edition 1998 The use of general descriptive names, registered names, trademarks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. Cover Design: Meta Design, Berlin Typesetting: perform k + s textdesign GmbH, Heidelberg SPIN 10567999
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Preface
Leafing through a journal of biology will almost certainly turn up several articles on some aspect of the eukaryotic cell division cycle. The progress in understanding the modus operandi of the cell cycle machinery and its central role in controlling cell proliferation has awakened a great deal of interest in many biologists. However, the cell cycle field often seems unnecessarily complicated, perhaps because data are acquired in bits and pieces and almost all simultaneously from studies using different systems and organisms. The aim of this book is to make the background of the cell cycle field as unambiguous and clear as possible by distinguishing what is commonly accepted in the field from what are the unsolved problems. Therefore, this book is intended to serve a large audience: graduate and postgraduate students, basic and clinical scientists involved in the study of cell growth, differentiation, senescence, apoptosis, and cancer. My hope is that this book will stimulate further interest in the fascinating field of the cell cycle and help scientists find connections between this and their fields of interest. This book brings together experts to review all major
