Cell Cycle in Development
This book focuses on the intersection between cell cycle regulation and embryo development. Specific modifications of the canonical cell cycle occur throughout the whole period of development and are adapted to fulfil functions coded by the developmental
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Series Editors Dietmar Richter, Henri Tiedge
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Jacek Z. Kubiak Editor
Cell Cycle in Development
Editor Jacek Z. Kubiak CNRS/University Rennes 1 UMR 6061, Institute of Genetics and Development of Rennes (IGDR) IFR 140 UEB Faculty of Medicine 2 Ave. du Prof. Leon Bernard 35043 Rennes Cedex France [email protected] Series Editors Dietmar Richter Center for Molecular Neurobiology University Medical Center HamburgEppendorf (UKE) University of Hamburg Martinistrasse 52 20246 Hamburg Germany [email protected]
Henri Tiedge The Robert F. Furchgott Center for Neural and Behavioral Science Department of Physiology and Pharmacology Department of Neurology SUNY Health Science Center at Brooklyn Brooklyn, New York 11203 USA [email protected]
ISBN 978-3-642-19064-3 e-ISBN 978-3-642-19065-0 DOI 10.1007/978-3-642-19065-0 Springer Heidelberg Dordrecht London New York Library of Congress Control Number: 2011929494 # Springer-Verlag Berlin Heidelberg 2011 This work is subject to copyright. All rights are reserved, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilm or in any other way, and storage in data banks. Duplication of this publication or parts thereof is permitted only under the provisions of the German Copyright Law of September 9, 1965, in its current version, and permission for use must always be obtained from Springer. Violations are liable to prosecution under the German Copyright Law. The use of general descriptive names, registered names, trademarks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. Cover design: WMXDesign GmbH, Heidelberg, Germany Printed on acid-free paper Springer is part of Springer Science+Business Media (www.springer.com)
Preface
The purpose of this volume is to give the readers a current vision of the whole panorama of cell cycle-related events implicated in animal development. To assure the highest scientific level of this review the very best experts in their respective fields were invited to participate in this adventure. All chapters were peer-reviewed, and special thanks are due to Takeo Kishimoto (Tokyo), Rafal Piprek (Krakow), Malathesha Ganachari (Houston), and Orna Halevy (Jerusalem) whose help was particularly important. The understanding of the specific mechanisms underlying the modifications of the cell cycle necessary to support development has a key role in comprehension of developmental processes. Specific adaptations of the cell cycle begin in unfertilized oocyte and occur throughout the whole embryonic and postnatal development. Even during senescence the cell cycle is modified in different tissues in a specific manner. Errors in these modifications may provoke pathologies. The cell cycle modification and adaptation to different developmental challenges are the le
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