Cellular and Molecular Aspects of Inflammation
The characterization of the cellular and molecular mechanisms that mediate inflammation provides a foundation that supports future studies that will de fine mechanisms more intimately. It encourages substantial optimism about the opportunities to underst
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NEW HORIZONS IN THERAPEUTICS Smith Kline & French Laboratories Research Symposia Series Series Editors: George Poste and Stanley T. Crooke Smith Kline & French Laboratories, Philadelphia, Pennsylvania
CELLULAR AND MOLECULAR ASPECTS OF INFLAMMATION Edited by George Poste and Stanley T. Crooke DOPAMINE RECEPTOR AGONISTS Edited by George Poste and Stanley T. Crooke MECHANISMS OF RECEPTOR REGULATION Edited by George Poste and Stanley T. Crooke NEW FRONTIERS IN THE STUDY OF GENE FUNCTIONS Edited by George Poste and Stanley T. Crooke NEW INSIGHTS INTO CELL AND MEMBRANE TRANSPORT PROCESSES Edited by George Poste and Stanley T. Crooke
Cellular and Molecular Aspects of Inflammation Edited by
GEORGE POSTE and STANLEY T. CROOKE
Smith Kline & French Laboratories Philadelphia, Pennsylvania
PLENUM PRESS • NEW YORK AND LONDON
Library of C6ngress Cataloging in Publication Data Cellular and molecular aspects of inflammation I edited by George Poste and Stanley T. Crooke. p. cm. - (New horizons in therapeutics) Proceedings of the 5th Smith, Kline, and French Research Symposium on New Horizons in Therapeutics, held in Philadelphia in 1987. Includes bibliographies and index. e-ISBN-13: 978-1-4684-5487-1 ISBN- 13: 978-1-4684-5489-5 DOl: 10.1007/978-1-4684-5487-1 1. Inflammation - Congresses. 2. Inflammtion - Mediators - Congresses. I. Poste, George. II. Crooke, Stanley T. III. Smith, Kline, and French Research Symposium on New Horizons in Therapeutics (5th: 1987: Philadelphia, Pa.) IV. Series. RB13I.C44 1988 616'.0473-dcl9 87-37400 CIP
© 1988 Plenum Press, New York Softcover reprint of the hardcover 15t edition 1988 A Division of Plenum Publishing Corporation 233" Spring Street, New York, N.Y. 10013 All rights reserved No part of this book may be reproduced, stored in a retrieval system, or transmitted in any form or by any means, electronic, mechanical, photocopying, microfilming, recording, or otherwise, without written permission from the Publisher
Contributors
Joanna Balcarek, Department of Molecular Pharmacology, Smith Kline & French Laboratories, Philadelphia, Pennsylvania 1910 I Vina.y S. Bansal, Division of Hematology-Oncology, Departments of Internal Medicine and Biological Chemistry, Washington University School of Medicine, St. Louis, Missouri 63110 Laurent Baud, Howard Hughes Medical Institute and Departments of Medicine and Microbiology-Immunology, University of California Medical Center, San Francisco, California 94143-0724 Robert M. Bell, Department of Biochemistry, Duke University Medical Center, Durham, North Carolina 27710 C. Frank Bennett, Department of Molecular Pharmacology, Smith Kline & French Laboratories, Philadelphia, Pennsylvania 19101
Druie Cavender, The University of Texas Health Science Center, Dallas, Texas 75235-9030 Anthony Cerami, Laboratory of Medical Biochemistry, The Rockefeller University, New York, New York 10021 M. K. William Chan, Department of Pathology, University of Toronto, Toronto, Ontario, Canada M5S lAS Mike Clark, Department of Molecular Pharmacology, Smith Kline & French L
