Characteristics of primary glomerular diseases patients with hematuria in Turkey: the data from TSN-GOLD Working Group
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NEPHROLOGY - ORIGINAL PAPER
Characteristics of primary glomerular diseases patients with hematuria in Turkey: the data from TSN‑GOLD Working Group Abdullah Sumnu1 · Kultigin Turkmen2 · Egemen Cebeci3 · Aydin Turkmen4 · Necmi Eren5 · Nurhan Seyahi6 · Aysegul Oruc7 · Fatih Dede8 · Ülver Derici9 · Taner Basturk10 · Garip Şahin11 · Murat Sipahioglu12 · Gulizar Manga Sahin13 · Erhan Tatar14 · Belda Dursun15 · Savas Sipahi16 · Mürvet Yılmaz17 · Gultekin Suleymanlar18 · Sena Ulu19 · Ozkan Gungor20 · Sim Kutlay21 · Zerrin Bicik Bahçebaşı22 · İdris Sahin23 · Ilhan Kurultak24 · Can Sevinc25 · Zulfikar Yilmaz26 · Rumeyza Turan Kazancioglu27 · Caner Cavdar28 · Ferhan Candan29 · Zeki Aydin30 · Deren Oygar31 · Bulent Gul32 · Bulent Altun33 · Saime Paydas34 · Sami Uzun3 · Zulal Istemihan35 · Metin Ergul5 · Mevlut Tamer Dincer6 · Mustafa Gullulu7 · Serhan Piskinpasa8 · Omer Faruk Akcay9 · Abdulkadir Unsal10 · Sumeyra Koyuncu12 · Mahmut Gok13 · Savas Ozturk3 Received: 29 May 2020 / Accepted: 27 October 2020 © Springer Nature B.V. 2020
Abstract Purpose Hematuria is one of the most common laboratory findings in nephrology practice. To date, there is no enough data regarding the clinical and histopathologic characteristics of primary glomerular disease (PGD) patients with hematuria in our country. Methods Data were obtained from national multicenter (47 centers) data entered into the Turkish Society of Nephrology Glomerular Diseases (TSN-GOLD) database between May 2009 and June 2019. The data of all PGD patients over the age of 16 years who were diagnosed with renal biopsy and had hematuria data were included in the study. Demographic characteristics, laboratory and biopsy findings were also recorded. Results Data of 3394 PGD patients were included in the study. While 1699 (50.1%) patients had hematuria, 1695 (49.9%) patients did not have hematuria. Patients with hematuria had statistically higher systolic blood pressure, serum blood urea nitrogen, creatinine, albumin, levels and urine pyuria. However, these patients had statistically lower age, body mass index, presence of hypertension and diabetes, eGFR, 24-h proteinuria, serum total, HDL and LDL cholesterol, and C3 levels when compared with patients without hematuria. Hematuria was present 609 of 1733 patients (35.8%) among the patients presenting with nephrotic syndrome, while it was presented in 1090 of 1661 (64.2%) patients in non-nephrotics (p 50% of glomeruli, which were identified
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International Urology and Nephrology
under light microscopy by the presence of at least two layers of cells in Bowman’s space. The patients’ data collected include age, gender, body mass index (BMI), blood pressure and laboratory parameters including hemogram, lipid profile, renal function tests, albumin, total protein, 24-h proteinuria, glucose, uric acid, calcium, alanine aminotransferase (ALT), erythrocyte sedimentation rate (ESR) and LM findings including tubular atrophy, interstitial fibrosis, number of total glomeruli, number of crescentic glomeruli, and number of sclerotic glome
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