Characterization of magnetic Fe 3 O 4 @SiO 2 nanoparticles with fluorescent properties for potential multipurpose imagin
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Characterization of magnetic Fe3O4@SiO2 nanoparticles with fluorescent properties for potential multipurpose imaging and theranostic applications Nurdan Kurnaz Yetim1,* Dilek Nartop3
, Fatma Kurs¸ un Baysak1, Mu¨min Mehmet Koc¸2, and
1
Department of Chemistry, Faculty of Arts and Sciences, Kırklareli University, Kırklareli, Turkey School of Medical Service, Kırklareli University, Kırklareli, Turkey 3 Department of Polymer Engineering, Faculty of Technology, Düzce University, Düzce, Turkey 2
Received: 22 July 2020
ABSTRACT
Accepted: 27 August 2020
Fe3O4 magnetic nanoparticles (MNPs) were produced using hydrothermal synthesis and coated with tetraethyl orthosilicate (TEOS) where Fe3O4@SiO2 MNPs with fluorescent properties were obtained. Structural characterization of the nanoparticles was performed using X-ray diffraction, scanning electron microscopy and transmission electron microscopy. Structural investigations confirmed that nanoparticles were in core@shell form. Chemical characterizations were performed using Fourier-transform infrared spectroscopy and energy-dispersive X-ray spectroscopy. Chemical investigations confirm that TEOS coating was successfully formed SiO2 shells on Fe3O4 nanoparticles. Magnetic characterizations revealed that nanoparticles show superparamagnetic properties which make them a suitable candidate for magnetic hyperthermia and magnetic resonance imaging (MRI) applications. Increased thickness of SiO2 shell in nanoparticle structure results in decreased magnetic saturation values. Fluorescence properties of the nanoparticles were confirmed using fluorescence spectroscopy. Increased SiO2 shell thickness results in increased fluorescent intensity. It was confirmed that Fe3O4@SiO2 nanoparticle has the potential to be used in medical applications such as MRI, fluorescence imaging and magnetic hyperthermia, and so on.
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Springer Science+Business
Media, LLC, part of Springer Nature 2020
1 Introduction Nanorange is a world that is full of surprises. Nanomaterials are building blocks of such a fascinating world and are under investigation of scientists
from different fields. Different properties of materials were revealed by scientists. Different parameters such as size, compound elements, structure, dimensions, and so on affect the properties and characteristics of the nanomaterials [1–4]. Metallic
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https://doi.org/10.1007/s10854-020-04375-7
J Mater Sci: Mater Electron
nanoparticles find immense areas of application. They present outstanding electrical, magnetic, and optic properties that can be tuned with small modifications [5–10]. Such properties can be applied to different fields such as cancer therapy, targeted drug delivery, biomarking, catalysis reactions, supercapacitors fuel cells, etc. [11–16]. Iron oxide nanoparticles have great potential to be used in industrial and medical applications [14]. Iron oxide nanoparticles have magnetic properties [17, 18]. They can show superparamagnetic or ferromagnetic charact
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