Chemistry and Brain Development Proceedings of the Advanced Study In
J. Folch-Pi Director of Scientific Research, McLean Hospital, Belmont, Mass., U.S.A. The development of the central nervous system is possibly the most significant aspect of the growth of a mammal from embryo to adulthood. The central nervous system is ob
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ADVANCES IN EXPERIMENTAL MEDICINE AND BIOLOGY Editorial Board: Nathan Back
Chairman, Department of Biochemical Pharmacology, School of Pharmacy, State University of New York, BuUalo, New York
N. R. Di Luzio
Chairman, Department of Physiology, Tulane University School of Medicine, New Orleans, Louisiana
Alfred Gellhorn
University of Pennsylvania Medical School, Philadelphia, Pennsylvania
Bernard Halpern
College de France. Director of the Institute of Immuno·Biology, Paris, France
Ephraim Katchalski
Department of Biophysics, The Weizmann Institute 01 Science, Rehovoth, Israel
David Kritchevsky
Wistar Institute, Philadelphia, Pennsylvania
Abel Lajtha
New York State Research Institute for Neurochemistry and Drug Addiction, Ward's Island, New York
Rodolfo Paoletti
Institute of Pharmacology, University of Milan, Milan,ltaly
Volume 1 THE RETICULOENDOTHELIAL SYSTEM AND ATHEROSCLEROSIS Edited by N. R. Di Luzio and R. Paoletti· 1967 Volume 2 PHARMACOLOGY OF HORMONAL POLYPEPTIDES AND PROTEINS Edited by N. Back, L. Martini, and R. Paoletti· 1968 Volume 3 GERM·FREE BIOLOGY-Experimental and Clinical Aspects Edited by E. A. Mirand and N. Back· 1969 Volume 4 DRUGS AFFECTING LIPID METABOLISM Edited by W. L. Holmes, L. A. Carlson, and R. Paoletti· 1969
Volume 8 BRADYKININ AND RELATED KININS: Cardiovascular, Biochemical, and Neural Actions Edited by F. Sicuteri, M. Rocha e Silva, and N. Back· 1970 Volume 9 SHOCK: Biochemical, Pharmacological, and Clinical Aspects Edited by A. Bertelli and N. Back· 1970 Volume 10 THE HUMAN TESTIS Edited by E. Rosemberg and C. A. Paulsen· 1970 Volume 11 MUSCLE METABOLISM DURING EXERCISE Edited by B. Pernow and B. Sahin • 1971
Volume 5 LYMPHATIC TISSUE AND GERMINAL CENTERS IN IMMUNE RESPONSE Edited by L. Fiore·Donati and M. G. Hanna, Jr.• 1969
Volume 12 MORPHOLOGICAL AND FUNCTIONAL ASPECTS OF IMMUNITY Edited by K. Lindahl.Kiessling, G. AIm, and M. G. Hanna, Jr.• 1971
Volume 6 RED CELL METABOLISM AND FUNCTION Edited by George J. Brewer· 1970
Volume 13 CHEMISTRY AND BRAIN DEVELOPMENT Edited by R. Paoletti and A. N. Davison '1971
Volume 7 SURFACE CHEMISTRY OF BIOLOGICAL SYSTEMS Edited by Marlin Blank· 1970
Volume 14 MEMBRANE·BOUND ENZYMES Edited by G. Porcellati and F. di Jeso • 1971
Chemistry and Brain Development Proceedings of the Advanced Study Institute on "Chemistry of Brain Development," held in Milan, Italy, September 9-19,1970
Edited by
Rodolfo Paoletti Chairman Institute of Pharmacology and Pharmacognosy University of Milan, Italy
Alan N. Davison Professor of Biochemistry Department of Biochemistry Charing Cross Hospital Medical School University of London, UK.
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PLENUM PRESS • NEW YORK· LONDON • 1971
Library of Congre88 Catalog Card Number 75·150494 SBN 306-39013-2
ISBN-13: 978-1-4684-7238-7 e-ISBN-13: 978-1-4684-7236-3 IK>I: 10.10071978-1-4684-7236-3 C 1971 PIe_ Preu, N8fI1 York ..4 Ditli&ion of Plenum Publiahing Corporation 227 Fat 17"'S&reee,N8fI1 York, N.Y. 10011
Softcover reprint of the hardcover 1st edition 1971 Unieed Kingdom edieion published by Plenu
