Cholesterol Interactions with Testosterone and Cortisol in Cardi
In 1935, Butenandt and Ruzicka received the Nobel Prize for synthesizing testosterone from cholesterol. Over the next few years, testosterone was used therapeutically by several clinicians, especially in Germany. However, with the outbreak of the Second W
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Cholesterol Interactions with Testosterone and Cortisol in Cardiovascular Diseases Foreword by Helge Einfeldt
With 4 Figures and 12 Color Photographs
Springer-Verlag Berlin Heidelberg New York London Paris Tokyo
Jens M011er President of the European Organization for the Control of Circulatory Diseases (EOCCD) Store Kongensgade 36 DK-1264 Copenhagen K
ISBN-13: 978-3-642-71602-7 DOl: 10.1007/978-3-642-71600-3
e-ISBN-13 978-3-642-71600-3
Library of Congress Cataloging-in-Publication Data. M0ller, Jens, 1904Cholesterol: interations with testosterone and cortisol in cardiovascular disease. Bibliography: p. Includes index. 1. Heart-Diseases-Chemotherapy. 2. IschemiaChemotherapy. 3. Testosterone-Therapeutic use. 4. Cholesterol. 5. Hydrocortisone. I. Title. [DNLM: 1. Cardiovascular Diseases-drug therapy. 2. Cholesterol-metabolism. 3. Hydrocortisonemetabolism. 4. Testosterone-therapeutic use. WG 166 M726c) RC684.T47M641987616.1'06186-28043 This work is subject to copyright. All rights are reserved, whether the whole or part of the material is concerned, specifically those of translation, reprinting, re-use of illustrations, broadcasting, reproduction by photocopying machine or similar means, and storage in data banks. Under § 54 of the German Copyright Law, where copies are made for other than private use, a fee is payable to "Verwertungsgesellschaft Wort", Munich. © by Springer-Verlag Berlin Heidelberg 1987
Softcover reprint of the hardcover I st edition 1987 The use of registered names, trademarks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. Product Liability: The publisher can give no guarantee for information about drug dosage and application therof contained in this book. In every individual case the respective user must check its accuracy by consulting other pharmaceutical literature. Media conversion: SB Datagraphics Ltd., Colchester Essex 2119/3140-543210
Foreword
In 1935, Butenandt and Ruzicka received the Nobel Prize for synthesizing testosterone from cholesterol. Over the next few years, testosterone was used therapeutically by several clinicians, especially in Germany. However, with the outbreak of the Second World War, international scientific research was effectively brought to an end. Using testosterone extracted from postmortem material, workers at the clinic of the famous Danish surgeon Thorkild Rovsing were able to show as early as the First World War that the substance had beneficial effects on cardiovascular disease. Given that this particularly important chapter in medical history opened in Copenhagen, it is appropriate that testosterone treatment was taken up in the 1950s by Jens Meller. During the 35 years since then, he has gained enormous experience in treating cardiovascular disease and is amply qualified to review the role testosterone has played in the more than ten thousand patients he has treated, most of them successfully. Many ha
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