Citalopram
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Citalopram Tourettism: case report A man [age stated to be 58-years-old; age at onset not clearly stated] developed tourettism during treatment with citalopram for depression. He presented with a 4-year history of abnormal neck movements and grunting. His symptoms started a few weeks after beginning citalopram treatment [route and dosage not stated]. Examination revealed stereotypic phonic and motor tics which were characterised by platysma muscle contraction, an inner build-up of an unpleasant sensation, and vocal grunting. At 3 months, his symptoms persisted, despite the withdrawal of citalopram. He was treated with pimozide but this was unable to control his tics. Tetrabenazine improved his symptoms. Author comment: "We hypothesized that citalopram is the cause for our patient’s de novo tic disorder, likely secondary to the increase in dopamine neurotransmitter caused by the SSRI." Ferreira MA, et al. A de novo case of tourettism caused by citalopram in an adult patient Movement Disorders 27 (Suppl. S1): abstr. 1328, Jun 2012. Available from: URL: http://onlinelibrary.wiley.com/doi/10.1002/mds.25051/pdf 803075164 USA
0114-9954/10/1414-0001/$14.95 Adis © 2010 Springer International Publishing AG. All rights reserved
Reactions 11 Aug 2012 No. 1414
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