Clinical and radiographic characteristics, management and short-term outcomes of patients with COVID-19 in Wenzhou, Chin
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RESEARCH ARTICLE
Open Access
Clinical and radiographic characteristics, management and short-term outcomes of patients with COVID-19 in Wenzhou, China Liang Hong1†, Enling Ye2†, Gangqiang Sun3†, Xiaoyang Wang4, Shengguo Zhang1, Yanghe Wu1, Xiangao Xie5, Shichun Xia6, Xudong Zheng7, Ling Dong8, Fujing Cai1, Xixian Lou8, Renguo Zhao8, Yongqi Hu7, Zhanwei Ruan7, Jiguang Ding1* and Qingfeng Sun1*
Abstract Background: Coronavirus disease 2019 (COVID-19) is an emerging viral disease. Here, we report the clinical features, management, and short-term outcomes of COVID-19 patients in Wenzhou, China, an area outside Wuhan. Methods: Patients admitted to the Infectious Diseases Department of Ruian People’s Hospital in Wenzhou, from January 21 to February 7, 2020, were recruited. Medical data on epidemiological history, demographics, clinical characteristics, laboratory tests, chest computerized tomography (CT) examination, treatment, and short-term outcomes were retrospectively reviewed. Blood biochemistry and routine tests were examined using standard methods and automatic machines. CT examination was performed several times during hospitalization as necessary. Results: A total of 67 confirmed COVID-19 cases were diagnosed; 64 (95.4%) were common cases and three (4.5%) were severe cases. The most common symptoms at admission were fever (86.6%), cough (77.6%), productive cough (52.2%), chest distress (17.9%), and sore throat (11.9%), followed by diarrhea (7.4%), headache (7.4%), shortness of breath (6.0%), dizziness (4.5%), muscular soreness (4.5%), and running nose (4.5%). Thirty patients (47.8%) had increased C-reactive protein levels. The CT radiographs at admission showed abnormal findings in 54 (80.6%) patients. The patients were treated mainly by oxygen therapy and antiviral drugs. By March 3, 2020, all 67 patients completely recovered and had negative nucleic acid tests. The patients were discharged from the hospital and transferred to a medical observation isolation center for further observation. Conclusion: Cases of COVID-19 in Wenzhou are milder and have a better prognosis, compared to those in Wuhan. Timely and appropriate screening, diagnosis, and treatment are the key to achieve good outcomes. Keywords: COVID-19, Clinical, Radiographic characteristics, SARS-cov-2, Epidemiology
* Correspondence: [email protected]; [email protected] † Liang Hong, Enling Ye and Gangqiang Sun contributed equally to this work. 1 Department of Infectious diseases, the Third Affiliated Hospital to Wenzhou Medical University (Ruian People’s Hospital), 108 Wansong Road, Ruian, Wenzhou 325200, Zhejiang Province, China Full list of author information is available at the end of the article © The Author(s). 2020 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indi
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