Clinical Characteristics and In-Hospital Mortality for COVID-19 Across The Globe
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BRIEF REPORT
Clinical Characteristics and In-Hospital Mortality for COVID-19 Across The Globe Sunny Goel . Tarun Jain . Amit Hooda . Rohit Malhotra . Gurpreet Johal . Reza Masoomi . Haroon Kamran . Parasuram Melarcode Krishnamoorthy . Nagendra Boopathy Senguttuvan . Abhishek Sharma . Umesh Gidwani
Received: June 3, 2020 Ó The Author(s) 2020
ABSTRACT Introduction: Numerous case series have reported on the baseline characteristics and inhospital mortality of patients with COVID-19, however, these studies included patients localized in a specific geographic region. The purpose of our study was to identify differences in the clinical characteristics and the in-hospital mortality of patients with a laboratory-confirmed diagnosis of COVID-19 internationally. Methods: A comprehensive search of all published literature on adult patients with laboratory-confirmed diagnosis of COVID-19 that reported on the clinical characteristics and inhospital mortality was performed. Groups were compared using a Chi-square test with Yates Digital features To view digital features for this article go to https://doi.org/10.6084/m9.figshare.12563726. S. Goel T. Jain A. Hooda R. Malhotra G. Johal R. Masoomi H. Kamran P. M. Krishnamoorthy N. B. Senguttuvan U. Gidwani Zena and Michael A. Wiener Cardiovascular Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA A. Sharma (&) Division of Cardiovascular Medicine, Gunderson Health System, La Crosse, WI, USA e-mail: [email protected] A. Sharma Institute of Cardiovascular Research and Technology, Brooklyn, NY, USA
correction of continuity. A two-tailed p value of less than 0.05 was considered as statistically significant. Results: After screening 516 studies across the globe, 43 studies from 12 countries were included in our final analysis. Patients with COVID19 in America and Europe were older compared to their Asian counterparts. Europe had the highest percentage of male patients. American and European patients had a higher incidence of co-morbid conditions (p \ 0.05 for all variables). In-hospital mortality was significantly higher in America (22.23%) and Europe (22.9%) compared to Asia (12.65%) (p \ 0.0001), but no difference was seen when compared with each other (p = 0.49). Conclusions: There is a significant variation in the clinical characteristics in patients diagnosed with COVID-19 across the globe. In-hospital mortality is similar between America and Europe, but considerably higher than Asia. Keywords: Clinical characteristics; COVID-19; In-hospital mortality
Cardiol Ther
Key Summary Points Why carry out this study? Numerous case series have reported on the baseline characteristics and in-hospital mortality of patients with COVID-19, however, these studies included patients localized in a specific geographic region. There is a significant variation in the clinical characteristics in patients diagnosed with COVID-19 across the globe. What was learned from the study? We found American and European patients diagnosed with COVID-19 a
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