Clinical Results of Fibroid Embolisation, Trials and Registries
Uterine fibroids are the most common tumour to affect women. Many are asymptomatic but when treatment is required there is almost always a choice. Uterine artery embolisation (UAE) is a relatively new minimally invasive technique and is usually one of the
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Contents 1
Introduction..........................................................................
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2 2.1 2.2 2.3
Evidence ................................................................................ EBM Pyramid ........................................................................ Levels of Evidence ................................................................ Grades of Recommendation (http://www.sign.ac.uk/ guidelines/fulltext/50/annexb.html).......................................
66 66 66
Outcome Measures ..............................................................
67
4 Systematic Reviews and Meta-Analyses ........................... 4.1 Cochrane Review................................................................... 4.2 Systematic Review and Meta-Analysis ................................
67 67 68
Trials ..................................................................................... PINTO.................................................................................... MARA.................................................................................... EMMY ................................................................................... REST...................................................................................... FUME .................................................................................... FEMME .................................................................................
68 68 68 68 69 69 70
6 Registries............................................................................... 6.1 U.S.A. Fibroid Registry......................................................... 6.2 BSIR/NICE UK Registry ......................................................
70 70 70
7 Cohort Studies...................................................................... 7.1 HOPEFUL..............................................................................
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8
Ovarian Function.................................................................
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9
Fertility and Pregnancy ......................................................
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10
Complications/Adverse Events ...........................................
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3
5 5.1 5.2 5.3 5.4 5.5 5.6
R. P. Yadavali Department of Radiology Aberdeen Royal Infirmary, Consultant Interventional Radiologist, Foresterhill, Aberdeen, AB25 2ZN, UK
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Deaths....................................................................................
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Cost-Effectiveness ................................................................
72
Abstract
Uterine fibroids are the most common tumour to affect women. Many are asymptomatic but when treatment is required there is almost always a choice. Uterine artery embolisation (UAE) is a relatively new minimally invasive technique and is usually one of the options. Initially slow to be accepted it is now a recognised, approved and funded procedure in most countries. It is the duty of any doctor to discuss all treatment options available with the patient. This discussion should be based
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