Clobetasol
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Clobetasol Majocchi granuloma in a patient with tinea incognito: case report A 29-year-old woman with tinea incognito developed Majocchi granuloma following treatment with clobetasol [Clobex]. The woman presented with a 4-month history of pruritic eruptions on her upper and lower extremities. She had been diagnosed with acute eczema, and treated with systemic and topical corticosteroids, including clobetasol 0.05%, for several months [dosage and time to reaction onset not stated]. However, the eruptions had worsened. On examination, multiple erythematous, scaling papules and plaques with crusts were evident on her arms and lower legs. Histology showed numerous arthrospores and hyphae within the hair follicles, and granulomatous infiltration of lymphocytes, histiocytes and giant cells was observed in the perifollicular area. Cultures grew spreading white colonies with golden-yellow reverse pigment and a cottony surface. Multiple fusiform and rough-walled macroconidias were evident upon lactophenol cotton blue staining. She was diagnosed with tinea incognito caused by Microsporum canis presenting as Majocchi granuloma. Mycological and clinical resolution were observed after 8 weeks of treatment with systemic and topical antifungals. Bae BG, et al. Majocchi granuloma caused by Microsporum canis as tinea incognito. Mycoses 54: 361-362, No. 4, Jul 2011. Available from: URL: http:// 803058738 dx.doi.org/10.1111/j.1439-0507.2010.01872.x - South Korea
0114-9954/10/1364-0001/$14.95 © 2010 Adis Data Information BV. All rights reserved
Reactions 13 Aug 2011 No. 1364
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