Cocaine and Other Stimulants

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ADVANCES IN BEHAVIORAL BIOLOGY Editorla' Board: Jan Bures Irwin Kopln Bruce McEwen James McGaugh Karl Prlbram Jay Rosenblatt Lawrence Welskrantz

Institute of Physiology, Prague, Czechoslovakia National Institute of Mental Health, Bethesda, Maryland Rockefeller University, New York, New York University of California, Irvine, California Stanford University School of Medicine, Stanford, California Rutgers University, Newark, New Jersey University of Oxford, Oxford, England

Recent Volumes in this Series Volume 10. NEUROHUMORAL CODING OF BRAIN FUNCTION Edited by R. D. Myers and Rene Raul Drucker·Colln. 1974 Volume 11 • REPRODUCTIVE BEHAVIOR Edited by William Montagna and William A. Sadler. 1974 Volume 12. THE NEUROPSYCHOLOGY OF AGGRESSION Edited by Richard E. Whalen. 1974 Volume 13. ANEURAL ORGANISMS IN NEUROBIOLOGY Edited by Edward M. Eisenstein. 1975 Volume 14. NUTRITION AND MENTAL FUNCTIONS Edited by George Serban • 1975 Volume 15 • SENSORY PHYSIOLOGY AND BEHAVIOR Edited by Rachel Galun, Peter Hillman, Itzhak Parnas, and Robert Werman. 1975 Volume 16. NEUROBIOLOGY OF AGING Edited by J. M. Ordy and K. R. Brizzee • 1975 Volume 17. ENVIRONMENTS AS THERAPY FOR BRAIN DYSFUNCTION Edited by Roger N. Walsh and William T. Greenough. 1976 Volume 18. NEURAL CONTROL OF LOCOMOTION Edited by Richard M. Herman, Sten Grillner, Paul S. G. Stein, and Douglas G. Stuart. 1976 Volume 19. THE BIOLOGY OF THE SCHIZOPHRENIC PROCESS Edited by Stewart Wolf and Beatrice Bishop Berle • 1976 Volume 20. THE SEPTAL NUCLEI Edited by Jon F. DeFrance. 1976 Volume 21 • COCAINE AND OTHER STIMULANTS Edited by Everett H. Ellinwood, Jr. and M. Marlyne Kilbey • 1977

A Continuation Order Plan is available for this series. A continuation order will bring delivery of each new volume immediately upon publication. Volumes are billed only upon actual shipment. For further information please contact the publisher.

Cocaine and Other Stimulants Edited by

Everett H. Ellinwood, Jr. and

M. Marlyne Kilbey Duke University Medical School

PLENUM PRESS • NEW YORK AND LONDON

Library of Congress Cataloging in Publication Data Main entry under title: Cocaine and other stimulants. (Advances in behavioral biology; v. 21' "Proceedings of a conference on contemporary issues in stimulant research held at Duke University Medical Center, Durham, North Carolina, November 10-12,1975." Includes indexes. 1. Cocaine-Physiological effect-Congresses. 2. Amphetamine-Physiological effect-Congresses. 3. Neuropsychopharmacology-Congresses. 4. Stimulants-Congresses. I. Ellinwood, Everett H. II. Kilbey, M. Marlyne. [DNLM: 1. Stimulation, Chemical-Congresses. 2. Cocaine-Pharmacodynamics-Congresses. QC113 C748c 1975] QP921.C7C59 615'.785 76-47488 e-ISBN-13: 978-1-4684-3087-5 ISBN-13: 978-1-4684-3089-9 001: 10.1007/978-1-4684-3087-5

Proceedings of a Conference on Contemporary Issues in Stimulant Research held at Duke University Medical Center, Durham, North Carolina, November 10-12, 1975

© 1977 Plenum Press, New York Softcover reprint of the hardcover 1st edition 1977 A Division of Plen