Stimulants
Underlying the design of the Handbook of Psychopharmacology is a prejudice that the study of drug influences on the mind has advanced to a stage where basic research and clinical application truly mesh. These later volumes of the Handbook are structured a
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Psychopharmacology Volume 11
Stimulants
Handbook of
Psychopharmacology SECTION I: BASIC NEUROPHARMACOLOGY Volume 1 Volume 2 Volume 3 Volume 4 Volume 5 Volume 6
Biochemical Principles and Techniques in Neuropharmacology Principles of Receptor Research Biochemistry of Biogenic Amines Amino Acid Neurotransmitters Synaptic Modulators Biogenic Amine Receptors
SECTION II: BEHAVIORAL PHARMACOLOGY IN ANIMALS Volume 7 Volume 8 Volume 9
Principles of Behavioral Pharmacology Drugs, Neurotransmitters, and Behavior Chemical Pathways in the Brain
SECTION III: HUMAN PSYCHOPHARMACOLOGY Volume 10 Volume 11 Volume 12 Volume 13 Volume 14
Neuroleptics and Schizophrenia Stimulants Drugs of Abuse Biology of Mood and Antianxiety Drugs Affective Disorders: Drug Actions in Animals and Man
Volume 11
Stimulants
Edited by
Leslie L. Iversen Department of Pharmacology University of Cambridge
Susan D. Iversen Department of Psychology University of Cam bridge
and
Solomon H. Snyder Departments of Pharmacology and Psychiatry The Johns Hopkins University School of Medicine
PLENUM PRESS • NEW YORK AND LONDON
Library of Congress Cataloging in Publication Data Main entry under title: Handbook of psychophannacology. Includes bibliographies and indexes. CONTENTS: v.I. Biochemical principles and techniques in neuropharmacology. -v. 2: Principles of receptor research. - v. 3. Biochemistry of biogenic amines. v. 4. Amino acid neurotransmitters. - v. 5. Synaptic modulators. - v. 6. Biogenic amine receptors. - v. 7. Principles of behavioral pharmacology. - v. 8. Drugs, Neurotransmitters, and Behavior. - v. 10 Neuroleptics and Schizophrenia. -. 11. Stimulants. 1. Psychopharmacology. I. Iversen, Leslie Lars. ll. Iversen Susan D., m: Snyder, Solomon H., 1938[DNLM: 1. Psychopharma1940· cology. QV77 H236] RC483.H36 615'.78 75-6851 ISBN 978-1-4757-0512-6 ISBN 978-1-4757-0510-2 (eBook) DOI 10.1007/978-1-4757-0510-2
© 1978 Plenum Press, New York
Softcover reprint of the hardcover 1st edition 1978 A Division of Plenum Publishing Corporation 227 West 17th Street, New York, N.Y. 10011 All rights reserved No part of this book may be reproduced, stored in a retrieval system, or transmitted, in any form or by any means, electronic, mechanical, photocopying, microfilming, recording or otherwise, without written permission from the Publisher
CONTRIBUTORS Neuropsychopharmacology Research Unit, Department if Psychiatry, New York University Medical Center, New York, New York J. H. BIEL (Deceased), Aldrich Chemical Company, Inc., Milwaukee, Wisconsin B. A. Bopp, Abbott Laboratories, North Chicago, Illinois NEAL CASTAGNOLI, JR., Department if Pharmaceutical Chemistry, School if Pharmacy, University if California, San Francisco, California ELLEN R. GRITZ, Veterans Administratzon Hospital Brentwood, and Department if Psychiatry, University of California, Los Angeles, California LEO E. HOLLISTER, Veterans Administration Hospital, and Stanford University School of Medicine, Palo Alto, California MURRAY E. JARVIK, Veterans Administration Hospital Brentwood,
