Coenzyme Q in Aging

This book offers a comprehensive exploration of research on the essential relationship of the coenzyme Q10 and the process of aging in living organisms. CoQ10 is an important factor in two main aspects of cell physiology: bioenergetics and antioxidant pro

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enzyme Q in Aging

Coenzyme Q in Aging

Guillermo López Lluch Editor

Coenzyme Q in Aging

Editor Guillermo López Lluch Physiology, Anatomy and Cell Biology Department Andalusian Center of Developmental Biology (CSIC-UPO), CIBERER Carlos III Health Institute Pablo de Olavide University Sevilla, Spain

ISBN 978-3-030-45641-2    ISBN 978-3-030-45642-9 (eBook) https://doi.org/10.1007/978-3-030-45642-9 © Springer Nature Switzerland AG 2020 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. The publisher, the authors, and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at the date of publication. Neither the publisher nor the authors or the editors give a warranty, expressed or implied, with respect to the material contained herein or for any errors or omissions that may have been made. The publisher remains neutral with regard to jurisdictional claims in published maps and institutional affiliations. This Springer imprint is published by the registered company Springer Nature Switzerland AG. The registered company address is: Gewerbestrasse 11, 6330 Cham, Switzerland

To my wife Araceli and my daughters Helena and Lucía. To the memory of my father and to my mother. Thanks for your effort to permit my education and formation. Dedications This book is dedicated to the memory of Fred L. Crane (December 3, 1925 – August 11, 2016). He discovered one of the most important molecules in organisms, Coenzyme Q10. After that, he worked hard in many other subjects to highlight the importance of this molecule till the end of his fruitful scientific life. In 1953, Fred Crane obtained his PhD in Botany from the University of Michigan, Ann Harbor. After that, he discovered coenzyme Q at the Institute of Enzyme Research, the University of Wisconsin, in 1957 (Crane et al, 1957 Isolation of a quinone from beef heart mitochondria. BBA 25: 220-221). His discovery started a long and productive scientific career with more than 400 papers. But the main characteristics of Fred Crane were his friendly character, his ability to

influence young scientists and to offer his enormous capacity to teach science, and his disposition to visit research institutes around the world sharing his expertise with other researchers. This great capacity helped him receive many awards including the American Chemical