Color Visual Evoked Potential Response for Myopia Subjects
Visual evoked potential (VEP) by checkerboard stimulation with red, green, and blue color for myopia subject was investigated. There are 10 subjects involved. The average VEP pattern derived from 100 times stimulation showed that peak N2 latency and peaks
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Abstract Visual evoked potential (VEP) by checkerboard stimulation with red, green, and blue color for myopia subject was investigated. There are 10 subjects involved. The average VEP pattern derived from 100 times stimulation showed that peak N2 latency and peaks P1 and P2 amplitude had significant variation among three colors. There was higher P2 amplitude response by red color than the other two colors. Myopia subjects without glasses had higher P1 and P2 amplitude response for green color. Keywords Visual evoked potential • Color • Myopia
1 Introduction Visual evoked potential (VEP) is often used to study visual processing mechanism under different physiological and psychological condition. Visual pathway under maturation and aging is also deeply investigated [1]. Different color stimulation had different response that is also proved as age-dependent changes during the schoolage period [2–4]. Different stimulation pattern also had effects on VEP pattern. For example, there is major VEP pattern on P100 and N145 peaks with checkerboard pattern [5]. Stimulation strength is also affected for VEP. Myopia subject without glasses was a suitable model to examine this phenomenon. Previous study had been
K.-M. Chang (*) Department of Photonics and Communication Engineering, Asia University, Taichung, Taiwan e-mail: [email protected] C.-Y. Tsai Department of Digital Media Design, Asia University, Taichung, Taiwan S.-H. Chen Department of Computer Science and Information Engineering, Asia University, Taichung, Taiwan J. Juang and Y.-C. Huang (eds.), Intelligent Technologies and Engineering Systems, Lecture Notes in Electrical Engineering 234, DOI 10.1007/978-1-4614-6747-2_23, # Springer Science+Business Media New York 2013
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investigated in the relation of binocular interaction with VEP [6]. This interesting study will investigate the basic VEP performance for three fundamental colors, red, green, and blue by checkerboard stimulation. Color areas were also important factor to be investigated. Color VEP response was also further applied for myopia subject.
2 Method 2.1
Subjects and EEG Recording
There were 10 volunteers mainly college students enrolled, 7 males and 3 females, age ranges 18–25 (mean age 22.4 and std 3.1). Subjects were all myopia patients. Subjects were sitting in a chair with comfortable posture. The EEG data was recorded in Asia University, Taiwan, by 32 channels SynAmps system produced by NeuroScan Inc. EEG data was recorded via unipolar connection, with Fpz as ground and A1/A2 as reference points. EEG channel impedance was adjusted until below 5 kΩ. A band-pass filter with 0.05–50 Hz was applied during recording. Sampling frequency was 1,000 Hz.
2.2
Experiment Procedures and Analysis
Experiment procedure was explained and under consent to each subject. There were 12 sessions in this study. The first nine sessions were applied to each subject with the aid of glasses. There are three colors combining with three check areas as experiment factors. Three colors are red,
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