Colorectal Cancer, Age, and Obesity-Related Comorbidities: A Large Database Study
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ORIGINAL ARTICLE
Colorectal Cancer, Age, and Obesity‑Related Comorbidities: A Large Database Study Abbinaya Elangovan1 · Jacob Skeans2 · Marc Landsman3 · Sajjadh M. J. Ali4 · Arvind Ganesan Elangovan5 · David C. Kaelber1 · Dalbir S. Sandhu6 · Gregory S. Cooper7 Received: 22 February 2020 / Accepted: 3 September 2020 © Springer Science+Business Media, LLC, part of Springer Nature 2020
Abstract Background and Aims The association between obesity and colorectal cancer (CRC) is well established in older individuals, but evidence is limited in the younger population. The study aims to analyze the relationship of obesity and its related comorbidities in early-onset CRC (E-CRC) and compare it to late-onset CRC (L-CRC). Methods A retrospective, cross-sectional study was performed on average-risk individuals ≥ 20 years who were active patients in the commercial database, IBM Watson Health Explorys in the last 5 years. Individuals with CRC were compared to those without CRC across different age groups (20–39, 40–49, and 50–74 years). Individuals with CRC diagnosed
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