Colorectal Cancer Screening
Colorectal Cancer Screening provides a complete overview of colorectal cancer screening, from epidemiology and molecular abnormalities, to the latest screening techniques such as stool DNA and FIT, Computerized Tomography (CT) Colonography, High Definitio
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Series Editor George Y. Wu University of Connecticut Health Center, Farmington, CT, USA
For further volumes: http://www.springer.com/series/7672
Joseph C. Anderson Charles J. Kahi ●
Editors
Colorectal Cancer Screening
Editors Joseph C. Anderson, MD Division of Gastroenterology University of Connecticut Health Center Colon Cancer Prevention Program Farmington, CT 06030-1845 USA [email protected]
Charles J. Kahi, MD Indiana University School of Medicine and Richard L. Roudebush VA Medical Center Indianapolis, IN 46202 USA [email protected]
ISBN 978-1-60761-397-8 e-ISBN 978-1-60761-398-5 DOI 10.1007/978-1-60761-398-5 Springer New York Dordrecht Heidelberg London Library of Congress Control Number: 2011924543 © Springer Science+Business Media, LLC 2011 All rights reserved. This work may not be translated or copied in whole or in part without the written permission of the publisher (Humana Press, c/o Springer Science+Business Media, LLC, 233 Spring Street, New York, NY 10013, USA), except for brief excerpts in connection with reviews or scholarly analysis. Use in connection with any form of information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed is forbidden. The use in this publication of trade names, trademarks, service marks, and similar terms, even if they are not identified as such, is not to be taken as an expression of opinion as to whether or not they are subject to proprietary rights. While the advice and information in this book are believed to be true and accurate at the date of going to press, neither the authors nor the editors nor the publisher can accept any legal responsibility for any errors or omissions that may be made. The publisher makes no warranty, express or implied, with respect to the material contained herein. Printed on acid-free paper Humana Press is part of Springer Science+Business Media (www.springer.com)
Preface
Colorectal cancer (CRC) is a major clinical and public health challenge; it is the third most common cancer and second leading cause of cancer deaths in the United States. Yet, CRC is a largely preventable disease. It has a long latency period, and it may be several years before a precursor polyp transforms into a malignant growth. These characteristics render CRC an attractive target for screening, both by detection of cancer at early, treatable stages, and more importantly, prevention by the timely detection and removal of precursor precancerous neoplasms. Recent multisociety guidelines have emphasized the central role of prevention in CRC screening strategies. The CRC screening landscape has undergone revolutionary changes over the past two decades, and remains a dynamic area at the interface of epidemiology, clinical research, outcomes research, public health, medical technology, and molecular and genetic science. The clinician who is considering CRC screening for a patient faces an array of options, considerations, and controversies which may be complex to navigate
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