Comparison of clinical diagnostic value of spiral CT with different dose in patients with early-stage peripheral lung ca
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RESEARCH ARTICLE
Comparison of clinical diagnostic value of spiral CT with different dose in patients with early‑stage peripheral lung cancer Y. J. Sun1 · J. Lou2 · Q. L. Xu3 · Y. G. Xing4 · X. Z. Zhao5 · L. L. Zhao6 · X. N. Wang7 Received: 13 May 2020 / Accepted: 15 September 2020 © Federación de Sociedades Españolas de Oncología (FESEO) 2020
Abstract Purpose To compare the clinical diagnostic value of spiral CT scan with different dose in patients with early-stage peripheral lung cancer. Methods A total of 163 cases of patients with early-stage peripheral lung cancer who came to People’s Hospital of Rizhao for treatment from June 2014 to January 2017 were retrospectively analyzed. A total of 78 cases of patients who received low-dose CT scanning were the low-dose group, another 84 cases of patients who received routine dose CT scanning were the routine dose group. Multislice helical CT (MSCT) scanning was performed in both groups, with tube voltage of 120 kV. Tube current was 25 m A in the low-dose group and 250 m A in the routine dose group. In addition, a total of 80 patients with lobar pneumonia were added as the control group of diagnostic sensitivity, specificity and accuracy. Pathological diagnosis was taken as the gold standard to compare the diagnostic sensitivity, specificity and accuracy of the two groups. Results The image quality, nodules and signs of the two groups were compared, and the results of radiation dose of the two groups were compared. The diagnostic sensitivity, specificity and accuracy of the low-dose group were 82.05%, 87.50% and 84.81%, respectively. The diagnostic sensitivity, specificity and accuracy of the routine dose group were 85.71%, 86.25% and 85.97%, respectively. The diagnostic value of the two groups was not statistically significant (p > 0.05). However, the radiation dose in the low-dose group was significantly lower than that in the routine group. Conclusion Low-dose MSCT scanning can meet the clinical requirements for imaging diagnosis of peripheral lung cancer, and can reduce the radiation dose of patients. Keywords Dose · Spiral CT · Early-stage peripheral lung cancer · Diagnostic value
Introduction Lung cancer (LC) is the main cause of cancer death worldwide. In 2012, a total of 1.8 million new LC cases were diagnosed globally, accounting for 13% all cancer diagnosed cases [1]. Because of reasons like tobacco and environmental Y. J. Sun and J. Lou contributed equally to this work. * X. N. Wang [email protected] 1
Department of Radiology, People’s Hospital of Rizhao, Rizhao 276826, People’s Republic of China
Department of General Surgery Ward, Jinan Zhangqiu District Hospital of TCM, Jinan 250200, People’s Republic of China
2
3
Health Care Ward, The People’s Hospital of Zhangqiu Area, Jinan 250200, People’s Republic of China
pollution, LC in the past few decades showed a trend of rapid growth [2, 3]. Most LC is already in the advanced stage when detected, and the prognosis of advanced LC is extremely poor and the survival rate is low [4]. Although th
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