Comparison of core-needle biopsy and repeat fine-needle aspiration for thyroid nodules with inconclusive initial cytolog
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Comparison of core‑needle biopsy and repeat fine‑needle aspiration for thyroid nodules with inconclusive initial cytology Seon Min Jung1 · Hye Ryoung Koo2 · Ki Seok Jang3 · Min Sung Chung4 · Chang Myeon Song1 · Yong Bae Ji1 · Jeong Seon Park2 · Kyung Tae1 Received: 21 September 2020 / Accepted: 2 November 2020 © Springer-Verlag GmbH Germany, part of Springer Nature 2020
Abstract Purpose We aimed to compare the efficacy of ultrasound-guided core-needle biopsy (CNB) with repeat fine-needle aspiration (rFNA) cytology in thyroid nodules with inconclusive results in initial fine-needle aspiration cytology. Methods We studied 402 patients who required a repeat biopsy of thyroid nodules using ultrasound-guided CNB (n = 192) or rFNA (n = 210) because of inconclusive results in initial FNA, corresponding to categories I, III, and IV of the Bethesda System for Reporting Thyroid Cytopathology. If repeat biopsy results were benign (category II), suspicious malignancy (category V), or malignancy (category VI), they were defined as “diagnostic results”. The diagnostic yield and performances of repeat biopsy were analyzed and compared between the rFNA and CNB groups. Results The diagnostic results were obtained significantly higher in the CNB group than in the rFNA group (72.4% vs. 52.4%; P
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