Comparison of numerical models for bulk and surface acoustic wave-induced acoustophoresis in a microchannel
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Comparison of numerical models for bulk and surface acoustic wave-induced acoustophoresis in a microchannel Yufeng Zhoua School of Mechanical and Aerospace Engineering, Nanyang Technological University, Singapore, Singapore Received: 4 February 2020 / Accepted: 14 August 2020 © Società Italiana di Fisica and Springer-Verlag GmbH Germany, part of Springer Nature 2020
Abstract Acoustophoresis induced by either bulk or surface acoustic wave has great potential to manipulate microparticles and biological substances because of its simple setup, low power consumption, and high generated force. Numerical models for simulating acoustophoresis in a microchannel are required to further understand the underlying mechanisms (i.e., standing acoustic wave and microparticle motion) and optimize the design. Simplified models that only consider the channel walls as actuation and impedance boundaries are available. In this study, full-sized models were established to include many phenomena and physical interactions involved and then compared with the simulation results using the simplified models. Distributions of acoustic pressure, streaming velocity, radiation force, and trajectory of 1 μm and 10 μm microparticles were calculated for further understanding of acoustofluidics. Overall, the full-sized models can provide an accurate guideline for the application and development of acoustophoresis.
1 Introduction Acoustofluidics has been emerging as an effective and precise tool for purely mechanical and label-free manipulation of microparticles and cell suspensions in lab-on-a-chip technologies [13, 23, 31]. It is a versatile tool that can address many limitations of other manipulation techniques. When a standing acoustic field is established in a microchannel, the particles are subject to the acoustic radiation force from the scattering of the acoustic waves and the Stokes drag force from the induced acoustic streaming flow. To produce the ultrasonic wave in the acoustofluidic channel one of the methods is the vibration of a piezoelectric material in either the thickness or shear modes, and such ultrasonic waves are referred as bulk acoustic wave (BAW) [10]. The other method developed in recent years is the surface acoustic wave (SAW)-based system. SAWs actuated on a piezoelectric substrate propagate along the surface and radiate into the coupling fluid. Acoustofluidic device can achieve many successful applications, such as separation lipid from blood [11, 24, 28], separation and
Electronic supplementary material The online version of this article (https://doi.org/10.1140/epjp/s1336 0-020-00697-x) contains supplementary material, which is available to authorized users. a e-mail: [email protected] (corresponding author)
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concentration of rare tumor cells from white blood cells [1, 30], and continuous separation of mixed particle suspensions into multiple outlet fractions [5, 6, 8, 23]. It has the advantages of simple architecture and high throughpu
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