Comparison of the effects of air-powder abrasion, chemical decontamination, or their combination in open-flap surface de
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ORIGINAL ARTICLE
Comparison of the effects of air-powder abrasion, chemical decontamination, or their combination in open-flap surface decontamination of implants failed for peri-implantitis: an ex vivo study Nicola Pranno 1 & Maria Paola Cristalli 2 & Fabio Mengoni 3 & Ilaria Sauzullo 3 & Susanna Annibali 1 & Antonella Polimeni 1 & Gerardo La Monaca 1 Received: 2 July 2020 / Accepted: 7 September 2020 # The Author(s) 2020
Abstract Objectives To compare, using an ex vivo model, the biofilm removal of three surface decontamination methods following surgical exposure of implants failed for severe peri-implantitis. Materials and methods The study design was a single-blind, randomized, controlled, ex vivo investigation with intra-subject control. Study participants were 20 consecutive patients with at least 4 hopeless implants, in function for >12 months and with progressive bone loss exceeding 50%, which had to be explanted. Implants of each patient were randomly assigned to the untreated control group or one of the three decontamination procedures: mechanical debridement with air-powder abrasion, chemical decontamination with hydrogen peroxide and chlorhexidine gluconate, or combined mechanical-chemical decontamination. Following surgical exposure, implants selected as control were retrieved, and afterwards, test implants were decontaminated according to allocation and carefully explanted with a removal kit. Microbiological analysis was expressed in colony-forming-units (CFU/ml). Results A statistically significant difference (p < 0.001) in the concentrations of CFU/ml was found between implants treated with mechanical debridement (531.58 ± 372.07) or combined mechanical-chemical decontamination (954.05 ± 2219.31) and implants untreated (37,800.00 ± 46,837.05) or treated with chemical decontamination alone (29,650.00 ± 42,596.20). No statistically significant difference (p = 1.000) was found between mechanical debridement used alone or supplemented with chemical decontamination. Microbiological analyses identified 21 microbial species, without significant differences between control and treatment groups. Conclusions Bacterial biofilm removal from infected implant surfaces was significantly superior for mechanical debridement than chemical decontamination. Clinical relevance The present is the only ex vivo study based on decontamination methods for removing actual and mature biofilm from infected implant surfaces in patients with peri-implantitis. Keywords Air-powder abrasion . Chemical decontamination . Peri-implantitis
Introduction * Maria Paola Cristalli [email protected] 1
Department of Oral and Maxillofacial Sciences, Sapienza University of Rome, Rome, Italy
2
Department of Biotechnologies and Medical Surgical Sciences, Sapienza University of Rome, 6. Caserta St., 00161 Rome, Italy
3
Department of Public Health and Infectious Diseases, Sapienza University of Rome, Rome, Italy
Implant therapy is an effective and predictable method to replace missing teeth with high long-term success and sur
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